Kostakis IK - Search Results

1

Antiproliferative and proapoptotic activities of pyranoxanthenones, pyranothioxanthenones and their pyrazole-fused derivatives in HL-60 cells.

Perchellet EM, Ward MM, Skaltsounis AL, Kostakis IK, Pouli N, Marakos P, Perchellet JP. Perchellet EM, et al. Among authors: kostakis ik. Anticancer Res. 2006 Jul-Aug;26(4B):2791-804. Anticancer Res. 2006. PMID: 16886598 Free article.

2

Mitochondria-Targeted Triphenylphosphonium-Hydroxytyrosol Prevents Lipotoxicity-Induced Endothelial Injury by Enhancing Mitochondrial Function and Redox Balance via Promoting FoxO1 and Nrf2 Nuclear Translocation and Suppressing Inflammation via Inhibiting p38/NF-кB Pathway.

Liu X, Gao J, Yan Y, Georgiou EA, Lou J, Feng M, Zhang X, Gao F, Liu J, Kostakis IK, Zhao L. Liu X, et al. Among authors: kostakis ik. Antioxidants (Basel). 2023 Jan 11;12(1):175. doi: 10.3390/antiox12010175. Antioxidants (Basel). 2023. PMID: 36671037 Free PMC article.

3

Synthesis and cytotoxic activity of 2-dialkylaminoethylamino substituted xanthenone and thioxanthenone derivatives.

Kostakis I, Ghirtis K, Pouli N, Marakos P, Skaltsounis AL, Leonce S, Caignard DH, Atassi G. Kostakis I, et al. Farmaco. 2000 Jun-Jul;55(6-7):455-60. doi: 10.1016/s0014-827x(00)00068-9. Farmaco. 2000. PMID: 11204746

4

Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones.

Kostakis IK, Pouli N, Marakos P, Mikros E, Skaltsounis AL, Leonce S, Atassi G, Renard P. Kostakis IK, et al. Bioorg Med Chem. 2001 Nov;9(11):2793-802. doi: 10.1016/s0968-0896(01)00130-4. Bioorg Med Chem. 2001. PMID: 11597459

5

Design and synthesis of some new pyranoxanthenone aminoderivatives with cytotoxic activity.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H. Kolokythas G, et al. Among authors: kostakis ik. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1443-6. doi: 10.1016/s0960-894x(02)00218-4. Bioorg Med Chem Lett. 2002. PMID: 12031316

6

Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino derivatives of the pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a new class of cytotoxic agents.

Kostakis IK, Magiatis P, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Léonce S, Pierré A. Kostakis IK, et al. J Med Chem. 2002 Jun 6;45(12):2599-609. doi: 10.1021/jm011117g. J Med Chem. 2002. PMID: 12036369

7

Synthesis and cytotoxic activity of some new azapyranoxanthenone aminoderivatives.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Kletsas D, Pratsinis H. Kolokythas G, et al. Among authors: kostakis ik. Bioorg Med Chem. 2003 Oct 15;11(21):4591-8. doi: 10.1016/s0968-0896(03)00503-0. Bioorg Med Chem. 2003. PMID: 14527556

8

Design, synthesis, and antiproliferative activity of some novel aminosubstituted xanthenones, able to overcome multidrug resistance toward MES-SA/Dx5 cells.

Kostakis IK, Tenta R, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Kletsas D. Kostakis IK, et al. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5057-60. doi: 10.1016/j.bmcl.2005.07.079. Bioorg Med Chem Lett. 2005. PMID: 16169719

9

Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D x 5 cells.

Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Kletsas D. Kostakis IK, et al. Bioorg Med Chem. 2006 May 1;14(9):2910-34. doi: 10.1016/j.bmc.2005.12.003. Epub 2006 Jan 11. Bioorg Med Chem. 2006. PMID: 16376546

10

Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: a new class of cytotoxic compounds.

Hadjipavlou C, Kostakis IK, Pouli N, Marakos P, Pratsinis H, Kletsas D. Hadjipavlou C, et al. Among authors: kostakis ik. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4822-5. doi: 10.1016/j.bmcl.2006.06.074. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16824751

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