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Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling.
Perchellet EM, Wang Y, Weber RL, Lou K, Hua DH, Perchellet JP. Perchellet EM, et al. Among authors: perchellet jp. Anticancer Drugs. 2004 Nov;15(10):929-46. doi: 10.1097/00001813-200411000-00002. Anticancer Drugs. 2004. PMID: 15514562
Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.
Perchellet JP, Perchellet EM, Singh CR, Monnett MT, Studer ER, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Buszek KR. Perchellet JP, et al. Among authors: perchellet em. Anticancer Res. 2014 Apr;34(4):1643-55. Anticancer Res. 2014. PMID: 24692693 Free PMC article.
69 results