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Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies.
Rowinsky EK, Humphrey R, Hammond LA, Aylesworth C, Smetzer L, Hidalgo M, Morrow M, Smith L, Garner A, Sorensen JM, Von Hoff DD, Eckhardt SG. Rowinsky EK, et al. Among authors: eckhardt sg. J Clin Oncol. 2000 Jan;18(1):178-86. doi: 10.1200/JCO.2000.18.1.178. J Clin Oncol. 2000. PMID: 10623708 Clinical Trial.
Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases.
Morelli MP, Cascone T, Troiani T, Tuccillo C, Bianco R, Normanno N, Romano M, Veneziani BM, Fontanini G, Eckhardt SG, De Pacido S, Tortora G, Ciardiello F. Morelli MP, et al. Among authors: eckhardt sg. J Cell Physiol. 2006 Aug;208(2):344-53. doi: 10.1002/jcp.20666. J Cell Physiol. 2006. PMID: 16688779
A phase I safety, pharmacological and biological study of the farnesyl protein transferase inhibitor, tipifarnib and capecitabine in advanced solid tumors.
Gore L, Holden SN, Cohen RB, Morrow M, Pierson AS, O'Bryant CL, Persky M, Gustafson D, Mikule C, Zhang S, Palmer PA, Eckhardt SG. Gore L, et al. Among authors: eckhardt sg. Ann Oncol. 2006 Nov;17(11):1709-17. doi: 10.1093/annonc/mdl282. Epub 2006 Sep 15. Ann Oncol. 2006. PMID: 16980604 Free article. Clinical Trial.
A phase I biological and pharmacologic study of the heparanase inhibitor PI-88 in patients with advanced solid tumors.
Basche M, Gustafson DL, Holden SN, O'Bryant CL, Gore L, Witta S, Schultz MK, Morrow M, Levin A, Creese BR, Kangas M, Roberts K, Nguyen T, Davis K, Addison RS, Moore JC, Eckhardt SG. Basche M, et al. Among authors: eckhardt sg. Clin Cancer Res. 2006 Sep 15;12(18):5471-80. doi: 10.1158/1078-0432.CCR-05-2423. Clin Cancer Res. 2006. PMID: 17000682 Clinical Trial.
Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors.
Hariharan S, Gustafson D, Holden S, McConkey D, Davis D, Morrow M, Basche M, Gore L, Zang C, O'Bryant CL, Baron A, Gallemann D, Colevas D, Eckhardt SG. Hariharan S, et al. Among authors: eckhardt sg. Ann Oncol. 2007 Aug;18(8):1400-7. doi: 10.1093/annonc/mdm140. Ann Oncol. 2007. PMID: 17693653 Free article. Clinical Trial.
362 results