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A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
Giles F, Fischer T, Cortes J, Garcia-Manero G, Beck J, Ravandi F, Masson E, Rae P, Laird G, Sharma S, Kantarjian H, Dugan M, Albitar M, Bhalla K. Giles F, et al. Among authors: laird g. Clin Cancer Res. 2006 Aug 1;12(15):4628-35. doi: 10.1158/1078-0432.CCR-06-0511. Clin Cancer Res. 2006. PMID: 16899611 Clinical Trial.
SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.
Farinre O, Anaya T, King AC, Endrias K, Hébert AH, Hill AL, Jean S, Wood JS, Ehnert S, Liang S, Laird GM, Mason RD, Roederer M, Safrit JT, Mavigner M, Chahroudi A. Farinre O, et al. Among authors: laird gm. PLoS Pathog. 2025 Jan 10;21(1):e1012863. doi: 10.1371/journal.ppat.1012863. Online ahead of print. PLoS Pathog. 2025. PMID: 39792949 Free article.
Single-cell analyses reveal that monocyte gene expression profiles influence HIV-1 reservoir size in acutely treated cohorts.
Ehrenberg PK, Geretz A, Volcic M, Izumi T, Yum L, Waickman A, Shangguan S, Paquin-Proulx D, Creegan M, Bose M, Machmach K, McGraw A, Narahari A, Currier JR, Sacdalan C, Phanuphak N, Apps R, Corley M, Ndhlovu LC, Slike B, Krebs SJ, Anonworanich J, Tovanabutra S, Robb ML, Eller MA, Laird GM, Cyktor J, Daar ES, Crowell TA, Mellors JW, Vasan S, Michael NL, Kirchhoff F, Thomas R. Ehrenberg PK, et al. Among authors: laird gm. bioRxiv [Preprint]. 2024 Nov 15:2024.11.12.623270. doi: 10.1101/2024.11.12.623270. bioRxiv. 2024. PMID: 39605411 Free PMC article. Preprint.
Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease.
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso MJ, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. Barbehenn A, et al. Among authors: laird gm. Nat Commun. 2024 Nov 18;15(1):9966. doi: 10.1038/s41467-024-54116-1. Nat Commun. 2024. PMID: 39557853 Free PMC article.
Galectin-9 Levels as a Potential Predictor of Intact HIV Reservoir Decay.
Serrano-Villar S, Gala A, Bacchetti P, Hoh R, di Germanio C, Cohn LB, Henrich TJ, Hunt PW, Laird GM, Pillai SK, Deeks SG, Peluso MJ. Serrano-Villar S, et al. Among authors: laird gm. J Infect Dis. 2024 Aug 28:jiae426. doi: 10.1093/infdis/jiae426. Online ahead of print. J Infect Dis. 2024. PMID: 39207259
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