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The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation.
Schaller S, Henriksen K, Sveigaard C, Heegaard AM, Hélix N, Stahlhut M, Ovejero MC, Johansen JV, Solberg H, Andersen TL, Hougaard D, Berryman M, Shiødt CB, Sørensen BH, Lichtenberg J, Christophersen P, Foged NT, Delaissé JM, Engsig MT, Karsdal MA. Schaller S, et al. Among authors: henriksen k. J Bone Miner Res. 2004 Jul;19(7):1144-53. doi: 10.1359/JBMR.040302. Epub 2004 Mar 1. J Bone Miner Res. 2004. PMID: 15176998 Free article.
Osteoclasts from patients with autosomal dominant osteopetrosis type I caused by a T253I mutation in low-density lipoprotein receptor-related protein 5 are normal in vitro, but have decreased resorption capacity in vivo.
Henriksen K, Gram J, Høegh-Andersen P, Jemtland R, Ueland T, Dziegiel MH, Schaller S, Bollerslev J, Karsdal MA. Henriksen K, et al. Am J Pathol. 2005 Nov;167(5):1341-8. doi: 10.1016/S0002-9440(10)61221-7. Am J Pathol. 2005. PMID: 16251418 Free PMC article.
438 results