DeBonis S - Search Results

1

Human kinetochore-associated kinesin CENP-E visualized at 17 A resolution bound to microtubules.

Neumann E, Garcia-Saez I, DeBonis S, Wade RH, Kozielski F, Conway JF. Neumann E, et al. Among authors: debonis s. J Mol Biol. 2006 Sep 15;362(2):203-11. doi: 10.1016/j.jmb.2006.07.042. Epub 2006 Jul 27. J Mol Biol. 2006. PMID: 16926026

2

Quaternary structure of casein kinase 2. Characterization of multiple oligomeric states and relation with its catalytic activity.

Valero E, De Bonis S, Filhol O, Wade RH, Langowski J, Chambaz EM, Cochet C. Valero E, et al. J Biol Chem. 1995 Apr 7;270(14):8345-52. doi: 10.1074/jbc.270.14.8345. J Biol Chem. 1995. PMID: 7713943 Free article.

3

Three-dimensional structure of functional motor proteins on microtubules.

Arnal I, Metoz F, DeBonis S, Wade RH. Arnal I, et al. Among authors: debonis s. Curr Biol. 1996 Oct 1;6(10):1265-70. doi: 10.1016/s0960-9822(02)70712-4. Curr Biol. 1996. PMID: 8939577 Free article.

4

The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations.

Kozielski F, De Bonis S, Burmeister WP, Cohen-Addad C, Wade RH. Kozielski F, et al. Structure. 1999 Nov 15;7(11):1407-16. doi: 10.1016/s0969-2126(00)80030-1. Structure. 1999. PMID: 10574799 Free article.

5

Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

DeBonis S, Simorre JP, Crevel I, Lebeau L, Skoufias DA, Blangy A, Ebel C, Gans P, Cross R, Hackney DD, Wade RH, Kozielski F. DeBonis S, et al. Biochemistry. 2003 Jan 21;42(2):338-49. doi: 10.1021/bi026716j. Biochemistry. 2003. PMID: 12525161 Free article.

6

In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities.

DeBonis S, Skoufias DA, Lebeau L, Lopez R, Robin G, Margolis RL, Wade RH, Kozielski F. DeBonis S, et al. Mol Cancer Ther. 2004 Sep;3(9):1079-90. Mol Cancer Ther. 2004. PMID: 15367702

7

Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.

Brier S, Lemaire D, Debonis S, Forest E, Kozielski F. Brier S, et al. Among authors: debonis s. Biochemistry. 2004 Oct 19;43(41):13072-82. doi: 10.1021/bi049264e. Biochemistry. 2004. PMID: 15476401

8

Essential kinesins: characterization of Caenorhabditis elegans KLP-15.

Robin G, DeBonis S, Dornier A, Cappello G, Ebel C, Wade RH, Thierry-Mieg D, Kozielski F. Robin G, et al. Among authors: debonis s. Biochemistry. 2005 May 3;44(17):6526-36. doi: 10.1021/bi048157h. Biochemistry. 2005. PMID: 15850386

9

Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5.

Brier S, Lemaire D, DeBonis S, Kozielski F, Forest E. Brier S, et al. Among authors: debonis s. Rapid Commun Mass Spectrom. 2006;20(3):456-62. doi: 10.1002/rcm.2329. Rapid Commun Mass Spectrom. 2006. PMID: 16402342

10

S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

Skoufias DA, DeBonis S, Saoudi Y, Lebeau L, Crevel I, Cross R, Wade RH, Hackney D, Kozielski F. Skoufias DA, et al. Among authors: debonis s. J Biol Chem. 2006 Jun 30;281(26):17559-69. doi: 10.1074/jbc.M511735200. Epub 2006 Feb 28. J Biol Chem. 2006. PMID: 16507573 Free article.

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