Pruimboom-Brees I - Search Results

1

A critical role for peroxisomal proliferator-activated receptor-alpha nuclear receptors in the development of cardiomyocyte degeneration and necrosis.

Pruimboom-Brees I, Haghpassand M, Royer L, Brees D, Aldinger C, Reagan W, Singh J, Kerlin R, Kane C, Bagley S, Hayward C, Loy J, O'Brien P, Francone OL. Pruimboom-Brees I, et al. Am J Pathol. 2006 Sep;169(3):750-60. doi: 10.2353/ajpath.2006.051110. Am J Pathol. 2006. PMID: 16936252 Free PMC article.

2

The PPARα agonists fenofibrate and CP-778875 cause increased β-oxidation, leading to oxidative injury in skeletal and cardiac muscle in the rat.

Pettersen JC, Pruimboom-Brees I, Francone OL, Amacher DE, Boldt SE, Kerlin RL, Ballinger WE. Pettersen JC, et al. Among authors: pruimboom brees i. Toxicol Pathol. 2012 Apr;40(3):435-47. doi: 10.1177/0192623311431945. Epub 2012 Feb 1. Toxicol Pathol. 2012. PMID: 22301950

3

Using laser scanning cytometry to measure PPAR-mediated peroxisome proliferation and beta oxidation.

Pruimboom-Brees IM, Brees DJ, Shen AC, Keener M, Francone O, Amacher DE, Loy JK, Kerlin RL. Pruimboom-Brees IM, et al. Toxicol Pathol. 2005;33(1):86-91. doi: 10.1080/01926230590881817. Toxicol Pathol. 2005. PMID: 15805059

4

The development of subcutaneous sarcomas in rodents exposed to peroxisome proliferators agonists: hypothetical mechanisms of action and de-risking attitude.

Pruimboom-Brees IM, Francone O, Pettersen JC, Kerlin RL, Will Y, Amacher DE, Boucher GG, Morton D. Pruimboom-Brees IM, et al. Toxicol Pathol. 2012 Jul;40(5):810-8. doi: 10.1177/0192623312441406. Epub 2012 Apr 13. Toxicol Pathol. 2012. PMID: 22504321

5

Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals.

O'Brien PJ, Smith DE, Knechtel TJ, Marchak MA, Pruimboom-Brees I, Brees DJ, Spratt DP, Archer FJ, Butler P, Potter AN, Provost JP, Richard J, Snyder PA, Reagan WJ. O'Brien PJ, et al. Lab Anim. 2006 Apr;40(2):153-71. doi: 10.1258/002367706776319042. Lab Anim. 2006. PMID: 16600075

6

Malignant astrocytoma with binucleated granular cells in a Sprague-Dawley rat.

Pruimboom-Brees IM, Brees DJ, Shen AC, Ibebunjo C. Pruimboom-Brees IM, et al. Vet Pathol. 2004 May;41(3):287-90. doi: 10.1354/vp.41-3-287. Vet Pathol. 2004. PMID: 15133182

7

The early effects of short-term dexamethasone administration on hepatic and serum alanine aminotransferase in the rat.

Jackson ER, Kilroy C, Joslin DL, Schomaker SJ, Pruimboom-Brees I, Amacher DE. Jackson ER, et al. Drug Chem Toxicol. 2008;31(4):427-45. doi: 10.1080/01480540802390247. Drug Chem Toxicol. 2008. PMID: 18850354

8

Proliferative and non-proliferative lesions of the rat and mouse soft tissue, skeletal muscle and mesothelium.

Greaves P, Chouinard L, Ernst H, Mecklenburg L, Pruimboom-Brees IM, Rinke M, Rittinghausen S, Thibault S, Von Erichsen J, Yoshida T. Greaves P, et al. Among authors: pruimboom brees im. J Toxicol Pathol. 2013;26(3 Suppl):1S-26S. doi: 10.1293/tox.26.1S. J Toxicol Pathol. 2013. PMID: 25035576 Free PMC article. Review.

9

PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy.

Jani JP, Arcari J, Bernardo V, Bhattacharya SK, Briere D, Cohen BD, Coleman K, Christensen JG, Emerson EO, Jakowski A, Hook K, Los G, Moyer JD, Pruimboom-Brees I, Pustilnik L, Rossi AM, Steyn SJ, Su C, Tsaparikos K, Wishka D, Yoon K, Jakubczak JL. Jani JP, et al. Among authors: pruimboom brees i. Mol Cancer Ther. 2010 Apr;9(4):883-94. doi: 10.1158/1535-7163.MCT-09-0915. Epub 2010 Mar 30. Mol Cancer Ther. 2010. PMID: 20354118

10

The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies.

Pullen N, Birch CL, Douglas GJ, Hussain Q, Pruimboom-Brees I, Walley RJ. Pullen N, et al. Among authors: pruimboom brees i. Hum Reprod Update. 2011 Nov-Dec;17(6):791-802. doi: 10.1093/humupd/dmr030. Epub 2011 Jul 6. Hum Reprod Update. 2011. PMID: 21733981 Review.

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