M-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced by cellular PIKE-A.
Werden SJ, Barrett JW, Wang G, Stanford MM, McFadden G.
Werden SJ, et al. Among authors: mcfadden g.
J Virol. 2007 Mar;81(5):2340-8. doi: 10.1128/JVI.01310-06. Epub 2006 Dec 6.
J Virol. 2007.
PMID: 17151107
Free PMC article.
The myxoma virus (MV) ankyrin repeat, host range factor M-T5 has the ability to bind and activate cellular Akt, leading to permissive MV replication in a variety of diverse human cancer cell lines (G. Wang, J. W. Barrett, M. Stanford, S. J. Werden, J. B. Johnston, X. Gao, …
The myxoma virus (MV) ankyrin repeat, host range factor M-T5 has the ability to bind and activate cellular Akt, leading to permissive MV rep …