Besada P - Search Results

1

Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor.

Besada P, Shin DH, Costanzi S, Ko H, Mathé C, Gagneron J, Gosselin G, Maddileti S, Harden TK, Jacobson KA. Besada P, et al. J Med Chem. 2006 Sep 7;49(18):5532-43. doi: 10.1021/jm060485n. J Med Chem. 2006. PMID: 16942026 Free PMC article.

2

Molecular recognition at purine and pyrimidine nucleotide (P2) receptors.

Jacobson KA, Costanzi S, Ohno M, Joshi BV, Besada P, Xu B, Tchilibon S. Jacobson KA, et al. Among authors: besada p. Curr Top Med Chem. 2004;4(8):805-19. doi: 10.2174/1568026043450961. Curr Top Med Chem. 2004. PMID: 15078212 Free PMC article. Review.

3

Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor.

Cattaneo M, Lecchi A, Ohno M, Joshi BV, Besada P, Tchilibon S, Lombardi R, Bischofberger N, Harden TK, Jacobson KA. Cattaneo M, et al. Among authors: besada p. Biochem Pharmacol. 2004 Nov 15;68(10):1995-2002. doi: 10.1016/j.bcp.2004.06.026. Biochem Pharmacol. 2004. PMID: 15476670 Free PMC article.

4

Molecular recognition at adenine nucleotide (P2) receptors in platelets.

Jacobson KA, Mamedova L, Joshi BV, Besada P, Costanzi S. Jacobson KA, et al. Among authors: besada p. Semin Thromb Hemost. 2005 Apr;31(2):205-16. doi: 10.1055/s-2005-869526. Semin Thromb Hemost. 2005. PMID: 15852224 Free PMC article. Review.

5

Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality.

Besada P, Mamedova L, Thomas CJ, Costanzi S, Jacobson KA. Besada P, et al. Org Biomol Chem. 2005 May 21;3(10):2016-25. doi: 10.1039/b416349d. Epub 2005 Apr 21. Org Biomol Chem. 2005. PMID: 15889186 Free PMC article.

6

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors.

Jacobson KA, Costanzi S, Ivanov AA, Tchilibon S, Besada P, Gao ZG, Maddileti S, Harden TK. Jacobson KA, et al. Among authors: besada p. Biochem Pharmacol. 2006 Feb 14;71(4):540-9. doi: 10.1016/j.bcp.2005.11.010. Epub 2005 Dec 15. Biochem Pharmacol. 2006. PMID: 16359641 Free PMC article.

7

Agonists and antagonists for P2 receptors.

Jacobson KA, Costanzi S, Joshi BV, Besada P, Shin DH, Ko H, Ivanov AA, Mamedova L. Jacobson KA, et al. Among authors: besada p. Novartis Found Symp. 2006;276:58-68; discussion 68-72, 107-12, 275-81. doi: 10.1002/9780470032244.ch6. Novartis Found Symp. 2006. PMID: 16805423 Free PMC article. Review.

8

Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.

Ivanov AA, Ko H, Cosyn L, Maddileti S, Besada P, Fricks I, Costanzi S, Harden TK, Calenbergh SV, Jacobson KA. Ivanov AA, et al. Among authors: besada p. J Med Chem. 2007 Mar 22;50(6):1166-76. doi: 10.1021/jm060903o. Epub 2007 Feb 16. J Med Chem. 2007. PMID: 17302398 Free PMC article.

9

Probing the binding site of the A1 adenosine receptor reengineered for orthogonal recognition by tailored nucleosides.

Palaniappan KK, Gao ZG, Ivanov AA, Greaves R, Adachi H, Besada P, Kim HO, Kim AY, Choe SA, Jeong LS, Jacobson KA. Palaniappan KK, et al. Among authors: besada p. Biochemistry. 2007 Jun 26;46(25):7437-48. doi: 10.1021/bi7001828. Epub 2007 Jun 2. Biochemistry. 2007. PMID: 17542617 Free PMC article.

10

Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation.

Gao ZG, Hechler B, Besada P, Gachet C, Jacobson KA. Gao ZG, et al. Among authors: besada p. Biochem Pharmacol. 2008 Mar 15;75(6):1341-7. doi: 10.1016/j.bcp.2007.10.037. Epub 2007 Dec 4. Biochem Pharmacol. 2008. PMID: 18199424 Free PMC article.

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