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Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum.
van Zandbergen G, Bollinger A, Wenzel A, Kamhawi S, Voll R, Klinger M, Müller A, Hölscher C, Herrmann M, Sacks D, Solbach W, Laskay T. van Zandbergen G, et al. Among authors: holscher c. Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13837-42. doi: 10.1073/pnas.0600843103. Epub 2006 Aug 31. Proc Natl Acad Sci U S A. 2006. PMID: 16945916 Free PMC article.
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A. Herrtwich L, et al. Among authors: holscher c. Cell. 2016 Nov 17;167(5):1264-1280.e18. doi: 10.1016/j.cell.2016.09.054. Epub 2016 Oct 27. Cell. 2016. PMID: 28084216 Free article.
Common patterns and disease-related signatures in tuberculosis and sarcoidosis.
Maertzdorf J, Weiner J 3rd, Mollenkopf HJ; TBornotTB Network; Bauer T, Prasse A, Müller-Quernheim J, Kaufmann SH. Maertzdorf J, et al. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7853-8. doi: 10.1073/pnas.1121072109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547807 Free PMC article.
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A. Herrtwich L, et al. Among authors: holscher c. Cell. 2018 Aug 23;174(5):1325-1326. doi: 10.1016/j.cell.2018.08.015. Cell. 2018. PMID: 30142346 Free article. No abstract available.
Monocyte progenitors give rise to multinucleated giant cells.
Lösslein AK, Lohrmann F, Scheuermann L, Gharun K, Neuber J, Kolter J, Forde AJ, Kleimeyer C, Poh YY, Mack M, Triantafyllopoulou A, Dunlap MD, Khader SA, Seidl M, Hölscher A, Hölscher C, Guan XL, Dorhoi A, Henneke P. Lösslein AK, et al. Among authors: holscher c, holscher a. Nat Commun. 2021 Apr 1;12(1):2027. doi: 10.1038/s41467-021-22103-5. Nat Commun. 2021. PMID: 33795674 Free PMC article.
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Kierdorf K, et al. Among authors: holscher c. Nat Neurosci. 2013 Mar;16(3):273-80. doi: 10.1038/nn.3318. Epub 2013 Jan 20. Nat Neurosci. 2013. PMID: 23334579
The increased protection and pathology in Mycobacterium tuberculosis-infected IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the IL-17A-induced expansion of multifunctional T cells.
Erdmann H, Behrends J, Ritter K, Hölscher A, Volz J, Rosenkrands I, Hölscher C. Erdmann H, et al. Among authors: holscher c, holscher a. Mucosal Immunol. 2018 Jul;11(4):1168-1180. doi: 10.1038/s41385-018-0026-3. Epub 2018 May 4. Mucosal Immunol. 2018. PMID: 29728641 Free article.
430 results