Pearl LH - Search Results

1

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity.

Doré AS, Kilkenny ML, Jones SA, Oliver AW, Roe SM, Bell SD, Pearl LH. Doré AS, et al. Among authors: pearl lh. Nucleic Acids Res. 2006;34(16):4515-26. doi: 10.1093/nar/gkl623. Epub 2006 Aug 31. Nucleic Acids Res. 2006. PMID: 16945955 Free PMC article.

2

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone.

Prodromou C, Roe SM, Piper PW, Pearl LH. Prodromou C, et al. Among authors: pearl lh. Nat Struct Biol. 1997 Jun;4(6):477-82. doi: 10.1038/nsb0697-477. Nat Struct Biol. 1997. PMID: 9187656

3

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone.

Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Prodromou C, et al. Among authors: pearl lh. Cell. 1997 Jul 11;90(1):65-75. doi: 10.1016/s0092-8674(00)80314-1. Cell. 1997. PMID: 9230303 Free article.

4

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo.

Panaretou B, Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Panaretou B, et al. Among authors: pearl lh. EMBO J. 1998 Aug 17;17(16):4829-36. doi: 10.1093/emboj/17.16.4829. EMBO J. 1998. PMID: 9707442 Free PMC article.

5

Crystal structure of an octameric RuvA-Holliday junction complex.

Roe SM, Barlow T, Brown T, Oram M, Keeley A, Tsaneva IR, Pearl LH. Roe SM, et al. Among authors: pearl lh. Mol Cell. 1998 Sep;2(3):361-72. doi: 10.1016/s1097-2765(00)80280-4. Mol Cell. 1998. PMID: 9774974 Free article.

6

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.

Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Roe SM, et al. Among authors: pearl lh. J Med Chem. 1999 Jan 28;42(2):260-6. doi: 10.1021/jm980403y. J Med Chem. 1999. PMID: 9925731

7

Crystal structure and induction mechanism of AmiC-AmiR: a ligand-regulated transcription antitermination complex.

O'Hara BP, Norman RA, Wan PT, Roe SM, Barrett TE, Drew RE, Pearl LH. O'Hara BP, et al. Among authors: pearl lh. EMBO J. 1999 Oct 1;18(19):5175-86. doi: 10.1093/emboj/18.19.5175. EMBO J. 1999. PMID: 10508151 Free PMC article.

8

Structural adaptation to selective pressure for altered ligand specificity in the Pseudomonas aeruginosa amide receptor, amiC.

O'Hara BP, Wilson SA, Lee AW, Roe SM, Siligardi G, Drew RE, Pearl LH. O'Hara BP, et al. Among authors: pearl lh. Protein Eng. 2000 Feb;13(2):129-32. doi: 10.1093/protein/13.2.129. Protein Eng. 2000. PMID: 10708652

9

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.

Prodromou C, Panaretou B, Chohan S, Siligardi G, O'Brien R, Ladbury JE, Roe SM, Piper PW, Pearl LH. Prodromou C, et al. Among authors: pearl lh. EMBO J. 2000 Aug 15;19(16):4383-92. doi: 10.1093/emboj/19.16.4383. EMBO J. 2000. PMID: 10944121 Free PMC article.

10

Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis.

Tan TH, Edgerton SA, Kumari R, McAlister MS, Roe SM, Nagl S, Pearl LH, Selkirk ME, Bianco AE, Totty NF, Engwerda C, Gray CA, Meyer DJ. Tan TH, et al. Among authors: pearl lh. Biochem J. 2001 Jul 15;357(Pt 2):373-83. doi: 10.1042/0264-6021:3570373. Biochem J. 2001. PMID: 11439086 Free PMC article.

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