Fidock DA - Search Results

1

PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.

Bray PG, Mungthin M, Hastings IM, Biagini GA, Saidu DK, Lakshmanan V, Johnson DJ, Hughes RH, Stocks PA, O'Neill PM, Fidock DA, Warhurst DC, Ward SA. Bray PG, et al. Among authors: fidock da. Mol Microbiol. 2006 Oct;62(1):238-51. doi: 10.1111/j.1365-2958.2006.05368.x. Epub 2006 Aug 31. Mol Microbiol. 2006. PMID: 16956382 Free PMC article.

2

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, Su XZ, Wootton JC, Roepe PD, Wellems TE. Fidock DA, et al. Mol Cell. 2000 Oct;6(4):861-71. doi: 10.1016/s1097-2765(05)00077-8. Mol Cell. 2000. PMID: 11090624 Free PMC article.

3

Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum.

Carlton JM, Fidock DA, Djimdé A, Plowe CV, Wellems TE. Carlton JM, et al. Among authors: fidock da. Curr Opin Microbiol. 2001 Aug;4(4):415-20. doi: 10.1016/s1369-5274(00)00228-9. Curr Opin Microbiol. 2001. PMID: 11495804 Review.

4

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Cooper RA, et al. Among authors: fidock da. Mol Pharmacol. 2002 Jan;61(1):35-42. doi: 10.1124/mol.61.1.35. Mol Pharmacol. 2002. PMID: 11752204

5

Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.

Bennett TN, Kosar AD, Ursos LM, Dzekunov S, Singh Sidhu AB, Fidock DA, Roepe PD. Bennett TN, et al. Among authors: fidock da. Mol Biochem Parasitol. 2004 Jan;133(1):99-114. doi: 10.1016/j.molbiopara.2003.09.008. Mol Biochem Parasitol. 2004. PMID: 14668017

6

Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Johnson DJ, Fidock DA, Mungthin M, Lakshmanan V, Sidhu AB, Bray PG, Ward SA. Johnson DJ, et al. Among authors: fidock da. Mol Cell. 2004 Sep 24;15(6):867-77. doi: 10.1016/j.molcel.2004.09.012. Mol Cell. 2004. PMID: 15383277 Free PMC article.

7

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance.

Bray PG, Martin RE, Tilley L, Ward SA, Kirk K, Fidock DA. Bray PG, et al. Among authors: fidock da. Mol Microbiol. 2005 Apr;56(2):323-33. doi: 10.1111/j.1365-2958.2005.04556.x. Mol Microbiol. 2005. PMID: 15813727 Free article. Review.

8

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.

Lakshmanan V, Bray PG, Verdier-Pinard D, Johnson DJ, Horrocks P, Muhle RA, Alakpa GE, Hughes RH, Ward SA, Krogstad DJ, Sidhu AB, Fidock DA. Lakshmanan V, et al. Among authors: fidock da. EMBO J. 2005 Jul 6;24(13):2294-305. doi: 10.1038/sj.emboj.7600681. Epub 2005 Jun 9. EMBO J. 2005. PMID: 15944738 Free PMC article.

9

pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum.

Sidhu AB, Valderramos SG, Fidock DA. Sidhu AB, et al. Among authors: fidock da. Mol Microbiol. 2005 Aug;57(4):913-26. doi: 10.1111/j.1365-2958.2005.04729.x. Mol Microbiol. 2005. PMID: 16091034 Free article.

10

Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+.

Biagini GA, Fidock DA, Bray PG, Ward SA. Biagini GA, et al. Among authors: fidock da. Antimicrob Agents Chemother. 2005 Nov;49(11):4807-8. doi: 10.1128/AAC.49.11.4807-4808.2005. Antimicrob Agents Chemother. 2005. PMID: 16251339 Free PMC article. No abstract available.

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