Chen B - Search Results

1

Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion.

Frey G, Rits-Volloch S, Zhang XQ, Schooley RT, Chen B, Harrison SC. Frey G, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13938-43. doi: 10.1073/pnas.0601036103. Epub 2006 Sep 8. Proc Natl Acad Sci U S A. 2006. PMID: 16963566 Free PMC article.

2

Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160.

Chen B, Zhou G, Kim M, Chishti Y, Hussey RE, Ely B, Skehel JJ, Reinherz EL, Harrison SC, Wiley DC. Chen B, et al. J Biol Chem. 2000 Nov 10;275(45):34946-53. doi: 10.1074/jbc.M004905200. J Biol Chem. 2000. PMID: 10944528 Free article.

3

The stoichiometry of trimeric SIV glycoprotein interaction with CD4 differs from that of anti-envelope antibody Fab fragments.

Kim M, Chen B, Hussey RE, Chishti Y, Montefiori D, Hoxie JA, Byron O, Campbell G, Harrison SC, Reinherz EL. Kim M, et al. Among authors: chen b. J Biol Chem. 2001 Nov 16;276(46):42667-76. doi: 10.1074/jbc.M104166200. Epub 2001 Sep 5. J Biol Chem. 2001. PMID: 11544255 Free article.

4

A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase.

Chen B, Cheng Y, Calder L, Harrison SC, Reinherz EL, Skehel JJ, Wiley DC. Chen B, et al. J Virol. 2004 May;78(9):4508-16. doi: 10.1128/jvi.78.9.4508-4516.2004. J Virol. 2004. PMID: 15078931 Free PMC article.

We have reported expression, purification, and characterization of gp140 (also called gp160e), the soluble, trimeric ectodomain of the SIV envelope glycoprotein, gp160 (B. Chen et al., J. Biol. Chem. 275:34946-34953, 2000). We have now expressed and purified chimeri …

We have reported expression, purification, and characterization of gp140 (also called gp160e), the soluble, trimeric ectodomain of the SIV e …

5

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC. Chen B, et al. Structure. 2005 Feb;13(2):197-211. doi: 10.1016/j.str.2004.12.004. Structure. 2005. PMID: 15698564 Free article.

6

Structure of an unliganded simian immunodeficiency virus gp120 core.

Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC. Chen B, et al. Nature. 2005 Feb 24;433(7028):834-41. doi: 10.1038/nature03327. Nature. 2005. PMID: 15729334

7

Restraining the conformation of HIV-1 gp120 by removing a flexible loop.

Rits-Volloch S, Frey G, Harrison SC, Chen B. Rits-Volloch S, et al. Among authors: chen b. EMBO J. 2006 Oct 18;25(20):5026-35. doi: 10.1038/sj.emboj.7601358. Epub 2006 Sep 28. EMBO J. 2006. PMID: 17006538 Free PMC article.

8

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies.

Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, Chen B. Frey G, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3739-44. doi: 10.1073/pnas.0800255105. Epub 2008 Mar 5. Proc Natl Acad Sci U S A. 2008. PMID: 18322015 Free PMC article.

9

Role of HIV membrane in neutralization by two broadly neutralizing antibodies.

Alam SM, Morelli M, Dennison SM, Liao HX, Zhang R, Xia SM, Rits-Volloch S, Sun L, Harrison SC, Haynes BF, Chen B. Alam SM, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20234-9. doi: 10.1073/pnas.0908713106. Epub 2009 Nov 11. Proc Natl Acad Sci U S A. 2009. PMID: 19906992 Free PMC article.

10

Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.

Frey G, Chen J, Rits-Volloch S, Freeman MM, Zolla-Pazner S, Chen B. Frey G, et al. Among authors: chen j, chen b. Nat Struct Mol Biol. 2010 Dec;17(12):1486-91. doi: 10.1038/nsmb.1950. Epub 2010 Nov 14. Nat Struct Mol Biol. 2010. PMID: 21076402 Free PMC article.

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