Lamar J - Search Results

1

Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile.

Xu Y, Etgen GJ, Broderick CL, Canada E, Gonzalez I, Lamar J, Montrose-Rafizadeh C, Oldham BA, Osborne JJ, Xie C, Shi Q, Winneroski LL, York J, Yumibe N, Zink R, Mantlo N. Xu Y, et al. Among authors: lamar j. J Med Chem. 2006 Sep 21;49(19):5649-52. doi: 10.1021/jm060617c. J Med Chem. 2006. PMID: 16970391

2

Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors.

Chen SH, Lamar J, Victor F, Snyder N, Johnson R, Heinz BA, Wakulchik M, Wang QM. Chen SH, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3531-6. doi: 10.1016/s0960-894x(03)00753-4. Bioorg Med Chem Lett. 2003. PMID: 14505664

3

Phe*-Ala-based pentapeptide mimetics are BACE inhibitors: P2 and P3 SAR.

Lamar J, Hu J, Bueno AB, Yang HC, Guo D, Copp JD, McGee J, Gitter B, Timm D, May P, McCarthy J, Chen SH. Lamar J, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):239-43. doi: 10.1016/j.bmcl.2003.09.084. Bioorg Med Chem Lett. 2004. PMID: 14684335

4

Discovery of a novel bicycloproline P2 bearing peptidyl alpha-ketoamide LY514962 as HCV protease inhibitor.

Yip Y, Victor F, Lamar J, Johnson R, Wang QM, Barket D, Glass J, Jin L, Liu L, Venable D, Wakulchik M, Xie C, Heinz B, Villarreal E, Colacino J, Yumibe N, Tebbe M, Munroe J, Chen SH. Yip Y, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2004 Jan 5;14(1):251-6. doi: 10.1016/j.bmcl.2003.09.074. Bioorg Med Chem Lett. 2004. PMID: 14684337

5

P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl alpha-ketoamide based HCV protease inhibitors.

Victor F, Lamar J, Snyder N, Yip Y, Guo D, Yumibe N, Johnson RB, Wang QM, Glass JI, Chen SH. Victor F, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2004 Jan 5;14(1):257-61. doi: 10.1016/j.bmcl.2003.09.075. Bioorg Med Chem Lett. 2004. PMID: 14684338

6

Novel P4 truncated tripeptidyl alpha-ketoamides as HCV protease inhibitors.

Lamar J, Victor F, Snyder N, Johnson RB, Wang QM, Glass JI, Chen SH. Lamar J, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):263-6. doi: 10.1016/j.bmcl.2003.09.076. Bioorg Med Chem Lett. 2004. PMID: 14684339

7

P4 cap modified tetrapeptidyl alpha-ketoamides as potent HCV NS3 protease inhibitors.

Sun DX, Liu L, Heinz B, Kolykhalov A, Lamar J, Johnson RB, Wang QM, Yip Y, Chen SH. Sun DX, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4333-8. doi: 10.1016/j.bmcl.2004.05.078. Bioorg Med Chem Lett. 2004. PMID: 15261297

8

P4 and P1' optimization of bicycloproline P2 bearing tetrapeptidyl alpha-ketoamides as HCV protease inhibitors.

Yip Y, Victor F, Lamar J, Johnson R, Wang QM, Glass JI, Yumibe N, Wakulchik M, Munroe J, Chen SH. Yip Y, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2004 Oct 4;14(19):5007-11. doi: 10.1016/j.bmcl.2004.07.007. Bioorg Med Chem Lett. 2004. PMID: 15341970

9

Design and synthesis of a novel class of dual PPARgamma/delta agonists.

Gonzalez IC, Lamar J, Iradier F, Xu Y, Winneroski LL, York J, Yumibe N, Zink R, Montrose-Rafizadeh C, Etgen GJ, Broderick CL, Oldham BA, Mantlo N. Gonzalez IC, et al. Among authors: lamar j. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1052-5. doi: 10.1016/j.bmcl.2006.11.029. Epub 2006 Nov 15. Bioorg Med Chem Lett. 2007. PMID: 17129725

10

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase.

Genin MJ, Gonzalez Valcarcel IC, Holloway WG, Lamar J, Mosior M, Hawkins E, Estridge T, Weidner J, Seng T, Yurek D, Adams LA, Weller J, Reynolds VL, Brozinick JT. Genin MJ, et al. Among authors: lamar j. J Med Chem. 2016 Jun 23;59(12):5904-10. doi: 10.1021/acs.jmedchem.5b01851. Epub 2016 Jun 6. J Med Chem. 2016. PMID: 27213958

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