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In vivo evidence of CHIP up-regulation attenuating tau aggregation.
Sahara N, Murayama M, Mizoroki T, Urushitani M, Imai Y, Takahashi R, Murata S, Tanaka K, Takashima A. Sahara N, et al. Among authors: takashima a. J Neurochem. 2005 Sep;94(5):1254-63. doi: 10.1111/j.1471-4159.2005.03272.x. J Neurochem. 2005. PMID: 16111477 Free article.
U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.
Hatakeyama S, Matsumoto M, Kamura T, Murayama M, Chui DH, Planel E, Takahashi R, Nakayama KI, Takashima A. Hatakeyama S, et al. Among authors: takashima a. J Neurochem. 2004 Oct;91(2):299-307. doi: 10.1111/j.1471-4159.2004.02713.x. J Neurochem. 2004. PMID: 15447663 Free article.
GSK-3beta is required for memory reconsolidation in adult brain.
Kimura T, Yamashita S, Nakao S, Park JM, Murayama M, Mizoroki T, Yoshiike Y, Sahara N, Takashima A. Kimura T, et al. Among authors: takashima a. PLoS One. 2008;3(10):e3540. doi: 10.1371/journal.pone.0003540. Epub 2008 Oct 28. PLoS One. 2008. PMID: 18958152 Free PMC article.
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
Takashima A, Murayama M, Murayama O, Kohno T, Honda T, Yasutake K, Nihonmatsu N, Mercken M, Yamaguchi H, Sugihara S, Wolozin B. Takashima A, et al. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9637-41. doi: 10.1073/pnas.95.16.9637. Proc Natl Acad Sci U S A. 1998. PMID: 9689133 Free PMC article.
756 results