Lifton RP - Search Results

1

WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters.

Kahle KT, Rinehart J, Ring A, Gimenez I, Gamba G, Hebert SC, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Physiology (Bethesda). 2006 Oct;21:326-35. doi: 10.1152/physiol.00015.2006. Physiology (Bethesda). 2006. PMID: 16990453 Free article. Review.

2

Human hypertension caused by mutations in WNK kinases.

Wilson FH, Disse-Nicodème S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP. Wilson FH, et al. Among authors: lifton rp. Science. 2001 Aug 10;293(5532):1107-12. doi: 10.1126/science.1062844. Science. 2001. PMID: 11498583

3

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP. Wilson FH, et al. Among authors: lifton rp. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):680-4. doi: 10.1073/pnas.242735399. Epub 2003 Jan 6. Proc Natl Acad Sci U S A. 2003. PMID: 12515852 Free PMC article.

4

WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia.

Choate KA, Kahle KT, Wilson FH, Nelson-Williams C, Lifton RP. Choate KA, et al. Among authors: lifton rp. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):663-8. doi: 10.1073/pnas.242728499. Epub 2003 Jan 8. Proc Natl Acad Sci U S A. 2003. PMID: 12522152 Free PMC article.

5

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.

Kahle KT, Wilson FH, Leng Q, Lalioti MD, O'Connell AD, Dong K, Rapson AK, MacGregor GG, Giebisch G, Hebert SC, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Nat Genet. 2003 Dec;35(4):372-6. doi: 10.1038/ng1271. Epub 2003 Nov 9. Nat Genet. 2003. PMID: 14608358

6

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.

Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2064-9. doi: 10.1073/pnas.0308434100. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769928 Free PMC article.

7

WNK kinases: molecular regulators of integrated epithelial ion transport.

Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Curr Opin Nephrol Hypertens. 2004 Sep;13(5):557-62. doi: 10.1097/00041552-200409000-00012. Curr Opin Nephrol Hypertens. 2004. PMID: 15300163 Review.

8

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.

Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14877-82. doi: 10.1073/pnas.0406172101. Epub 2004 Oct 1. Proc Natl Acad Sci U S A. 2004. PMID: 15465913 Free PMC article.

9

Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch.

Kahle KT, Wilson FH, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Trends Endocrinol Metab. 2005 Apr;16(3):98-103. doi: 10.1016/j.tem.2005.02.012. Trends Endocrinol Metab. 2005. PMID: 15808806 Review.

10

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.

Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP. Kahle KT, et al. Among authors: lifton rp. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16783-8. doi: 10.1073/pnas.0508307102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275911 Free PMC article.

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