Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein.
Brechler V, Pavoine C, Hanf R, Garbarz E, Fischmeister R, Pecker F.
Brechler V, et al. Among authors: fischmeister r.
J Biol Chem. 1992 Aug 5;267(22):15496-501.
J Biol Chem. 1992.
PMID: 1353495
Free article.
F., Brechler, V., Pavoine, C., Pecker, F., and Fischmeister, R. (1990) Nature 345, 158-161). We show here that the inhibition of membrane-bound PDE activity by glucagon depends on guanine nucleotides, a reproducible inhibition of 40% being obtained with 0.1 microM g …
F., Brechler, V., Pavoine, C., Pecker, F., and Fischmeister, R. (1990) Nature 345, 158-161). We show here that the inhibition …