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WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.
Brandenburg J, Marwitz S, Tazoll SC, Waldow F, Kalsdorf B, Vierbuchen T, Scholzen T, Gross A, Goldenbaum S, Hölscher A, Hein M, Linnemann L, Reimann M, Kispert A, Leitges M, Rupp J, Lange C, Niemann S, Behrends J, Goldmann T, Heine H, Schaible UE, Hölscher C, Schwudke D, Reiling N. Brandenburg J, et al. Among authors: leitges m. J Clin Invest. 2021 Aug 16;131(16):e141833. doi: 10.1172/JCI141833. J Clin Invest. 2021. PMID: 34255743 Free PMC article.
PKC-beta is not necessary for cardiac hypertrophy.
Roman BB, Geenen DL, Leitges M, Buttrick PM. Roman BB, et al. Among authors: leitges m. Am J Physiol Heart Circ Physiol. 2001 May;280(5):H2264-70. doi: 10.1152/ajpheart.2001.280.5.H2264. Am J Physiol Heart Circ Physiol. 2001. PMID: 11299230 Free article.
Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.
Kenchappa RS, Liu Y, Argenziano MG, Banu MA, Mladek AC, West R, Luu A, Quiñones-Hinojosa A, Hambardzumyan D, Justilien V, Leitges M, Sarkaria JN, Sims PA, Canoll P, Murray NR, Fields AP, Rosenfeld SS. Kenchappa RS, et al. Among authors: leitges m. Cell Rep. 2021 Nov 23;37(8):110054. doi: 10.1016/j.celrep.2021.110054. Cell Rep. 2021. PMID: 34818553 Free PMC article.
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.
Bezy O, Tran TT, Pihlajamäki J, Suzuki R, Emanuelli B, Winnay J, Mori MA, Haas J, Biddinger SB, Leitges M, Goldfine AB, Patti ME, King GL, Kahn CR. Bezy O, et al. Among authors: leitges m. J Clin Invest. 2011 Jun;121(6):2504-17. doi: 10.1172/JCI46045. Epub 2011 May 16. J Clin Invest. 2011. PMID: 21576825 Free PMC article.
236 results