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Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training.
Burns N, Finucane FM, Hatunic M, Gilman M, Murphy M, Gasparro D, Mari A, Gastaldelli A, Nolan JJ. Burns N, et al. Among authors: nolan jj. Diabetologia. 2007 Jul;50(7):1500-8. doi: 10.1007/s00125-007-0655-7. Epub 2007 Mar 29. Diabetologia. 2007. PMID: 17393133 Free article.
An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial.
O'Donoghue GM, Kennedy A, Andersen GS, Durkan E, Thybo T, Sinnott M, Nolan JJ, O'Gorman DJ. O'Donoghue GM, et al. Among authors: nolan jj. Trials. 2015 Nov 18;16:529. doi: 10.1186/s13063-015-1042-1. Trials. 2015. PMID: 26581687 Free PMC article. Clinical Trial.
Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism.
Hernández-Alvarez MI, Díaz-Ramos A, Berdasco M, Cobb J, Planet E, Cooper D, Pazderska A, Wanic K, O'Hanlon D, Gomez A, de la Ballina LR, Esteller M, Palacin M, O'Gorman DJ, Nolan JJ, Zorzano A. Hernández-Alvarez MI, et al. Among authors: nolan jj. Sci Rep. 2017 Oct 23;7(1):13850. doi: 10.1038/s41598-017-14120-6. Sci Rep. 2017. PMID: 29062026 Free PMC article.
Insulin sensitivity depends on the route of glucose administration.
Mingrone G, Panunzi S, De Gaetano A, Ahlin S, Spuntarelli V, Bondia-Pons I, Barbieri C, Capristo E, Gastaldelli A, Nolan JJ. Mingrone G, et al. Among authors: nolan jj. Diabetologia. 2020 Jul;63(7):1382-1395. doi: 10.1007/s00125-020-05157-w. Epub 2020 May 8. Diabetologia. 2020. PMID: 32385603 Free PMC article.
Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals.
Finucane FM, Luan J, Wareham NJ, Sharp SJ, O'Rahilly S, Balkau B, Flyvbjerg A, Walker M, Højlund K, Nolan JJ; (on behalf of the European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk Study Group); Savage DB. Finucane FM, et al. Among authors: nolan jj. Diabetologia. 2009 Nov;52(11):2345-2349. doi: 10.1007/s00125-009-1508-3. Epub 2009 Sep 12. Diabetologia. 2009. PMID: 19756488 Free PMC article.
127 results