Remaut E - Search Results

1

Intracellular accumulation of trehalose protects Lactococcus lactis from freeze-drying damage and bile toxicity and increases gastric acid resistance.

Termont S, Vandenbroucke K, Iserentant D, Neirynck S, Steidler L, Remaut E, Rottiers P. Termont S, et al. Among authors: remaut e. Appl Environ Microbiol. 2006 Dec;72(12):7694-700. doi: 10.1128/AEM.01388-06. Epub 2006 Oct 6. Appl Environ Microbiol. 2006. PMID: 17028239 Free PMC article.

2

Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice.

Vandenbroucke K, Hans W, Van Huysse J, Neirynck S, Demetter P, Remaut E, Rottiers P, Steidler L. Vandenbroucke K, et al. Among authors: remaut e. Gastroenterology. 2004 Aug;127(2):502-13. doi: 10.1053/j.gastro.2004.05.020. Gastroenterology. 2004. PMID: 15300583

3

Development of an enteric-coated formulation containing freeze-dried, viable recombinant Lactococcus lactis for the ileal mucosal delivery of human interleukin-10.

Huyghebaert N, Vermeire A, Neirynck S, Steidler L, Remaut E, Remon JP. Huyghebaert N, et al. Among authors: remaut e. Eur J Pharm Biopharm. 2005 Aug;60(3):349-59. doi: 10.1016/j.ejpb.2005.02.012. Eur J Pharm Biopharm. 2005. PMID: 15927456

4

Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10.

Steidler L, Neirynck S, Huyghebaert N, Snoeck V, Vermeire A, Goddeeris B, Cox E, Remon JP, Remaut E. Steidler L, et al. Among authors: remaut e. Nat Biotechnol. 2003 Jul;21(7):785-9. doi: 10.1038/nbt840. Epub 2003 Jun 15. Nat Biotechnol. 2003. PMID: 12808464

5

Development of an enteric-coated, layered multi-particulate formulation for ileal delivery of viable recombinant Lactococcus lactis.

Huyghebaert N, Vermeire A, Rottiers P, Remaut E, Remon JP. Huyghebaert N, et al. Among authors: remaut e. Eur J Pharm Biopharm. 2005 Oct;61(3):134-41. doi: 10.1016/j.ejpb.2005.04.002. Epub 2005 Jun 20. Eur J Pharm Biopharm. 2005. PMID: 15967652

6

A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease.

Braat H, Rottiers P, Hommes DW, Huyghebaert N, Remaut E, Remon JP, van Deventer SJ, Neirynck S, Peppelenbosch MP, Steidler L. Braat H, et al. Among authors: remaut e. Clin Gastroenterol Hepatol. 2006 Jun;4(6):754-9. doi: 10.1016/j.cgh.2006.03.028. Epub 2006 May 22. Clin Gastroenterol Hepatol. 2006. PMID: 16716759 Clinical Trial.

7

Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis.

Coppieters K, Dreier T, Silence K, de Haard H, Lauwereys M, Casteels P, Beirnaert E, Jonckheere H, Van de Wiele C, Staelens L, Hostens J, Revets H, Remaut E, Elewaut D, Rottiers P. Coppieters K, et al. Among authors: remaut e. Arthritis Rheum. 2006 Jun;54(6):1856-66. doi: 10.1002/art.21827. Arthritis Rheum. 2006. PMID: 16736523 Free article.

8

Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?

Breyer D, Herman P, Brandenburger A, Gheysen G, Remaut E, Soumillion P, Van Doorsselaere J, Custers R, Pauwels K, Sneyers M, Reheul D. Breyer D, et al. Among authors: remaut e. Environ Biosafety Res. 2009 Apr-Jun;8(2):57-64. doi: 10.1051/ebr/2009007. Epub 2009 Oct 16. Environ Biosafety Res. 2009. PMID: 19833073 Free article.

9

Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis.

Vandenbroucke K, de Haard H, Beirnaert E, Dreier T, Lauwereys M, Huyck L, Van Huysse J, Demetter P, Steidler L, Remaut E, Cuvelier C, Rottiers P. Vandenbroucke K, et al. Among authors: remaut e. Mucosal Immunol. 2010 Jan;3(1):49-56. doi: 10.1038/mi.2009.116. Epub 2009 Sep 30. Mucosal Immunol. 2010. PMID: 19794409 Free article.

10

Genetically engineered Lactococcus lactis secreting murine IL-10 modulates the functions of bone marrow-derived dendritic cells in the presence of LPS.

Loos M, Remaut E, Rottiers P, De Creus A. Loos M, et al. Among authors: remaut e. Scand J Immunol. 2009 Feb;69(2):130-9. doi: 10.1111/j.1365-3083.2008.02206.x. Epub 2008 Dec 22. Scand J Immunol. 2009. PMID: 19144079 Free article.

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