Walsh CT - Search Results

1

Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry.

Dorrestein PC, Bumpus SB, Calderone CT, Garneau-Tsodikova S, Aron ZD, Straight PD, Kolter R, Walsh CT, Kelleher NL. Dorrestein PC, et al. Among authors: walsh ct. Biochemistry. 2006 Oct 24;45(42):12756-66. doi: 10.1021/bi061169d. Biochemistry. 2006. PMID: 17042494 Free PMC article.

2

MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli.

Brown ED, Vivas EI, Walsh CT, Kolter R. Brown ED, et al. Among authors: walsh ct. J Bacteriol. 1995 Jul;177(14):4194-7. doi: 10.1128/jb.177.14.4194-4197.1995. J Bacteriol. 1995. PMID: 7608103 Free PMC article.

3

From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase.

Li YM, Milne JC, Madison LL, Kolter R, Walsh CT. Li YM, et al. Among authors: walsh ct. Science. 1996 Nov 15;274(5290):1188-93. doi: 10.1126/science.274.5290.1188. Science. 1996. PMID: 8895467

4

Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetase.

Weinreb PH, Quadri LE, Walsh CT, Zuber P. Weinreb PH, et al. Among authors: walsh ct. Biochemistry. 1998 Feb 10;37(6):1575-84. doi: 10.1021/bi9719859. Biochemistry. 1998. PMID: 9484228

5

Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases.

Quadri LE, Weinreb PH, Lei M, Nakano MM, Zuber P, Walsh CT. Quadri LE, et al. Among authors: walsh ct. Biochemistry. 1998 Feb 10;37(6):1585-95. doi: 10.1021/bi9719861. Biochemistry. 1998. PMID: 9484229

6

Kinetics and regioselectivity of peptide-to-heterocycle conversions by microcin B17 synthetase.

Belshaw PJ, Roy RS, Kelleher NL, Walsh CT. Belshaw PJ, et al. Among authors: walsh ct. Chem Biol. 1998 Jul;5(7):373-84. doi: 10.1016/s1074-5521(98)90071-0. Chem Biol. 1998. PMID: 9662507

7

ATP/GTP hydrolysis is required for oxazole and thiazole biosynthesis in the peptide antibiotic microcin B17.

Milne JC, Eliot AC, Kelleher NL, Walsh CT. Milne JC, et al. Among authors: walsh ct. Biochemistry. 1998 Sep 22;37(38):13250-61. doi: 10.1021/bi980996e. Biochemistry. 1998. PMID: 9748332

8

Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17.

Milne JC, Roy RS, Eliot AC, Kelleher NL, Wokhlu A, Nickels B, Walsh CT. Milne JC, et al. Among authors: walsh ct. Biochemistry. 1999 Apr 13;38(15):4768-81. doi: 10.1021/bi982975q. Biochemistry. 1999. PMID: 10200165

9

In vivo processing and antibiotic activity of microcin B17 analogs with varying ring content and altered bisheterocyclic sites.

Sinha Roy R, Kelleher NL, Milne JC, Walsh CT. Sinha Roy R, et al. Among authors: walsh ct. Chem Biol. 1999 May;6(5):305-18. doi: 10.1016/s1074-5521(99)80076-3. Chem Biol. 1999. PMID: 10322125

10

Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization.

Shaw-Reid CA, Kelleher NL, Losey HC, Gehring AM, Berg C, Walsh CT. Shaw-Reid CA, et al. Among authors: walsh ct. Chem Biol. 1999 Jun;6(6):385-400. doi: 10.1016/S1074-5521(99)80050-7. Chem Biol. 1999. PMID: 10375542

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