Handratta VD - Search Results

1

Regulation of androgen receptor activity by tyrosine phosphorylation.

Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O, Nesheiwat I, Kong X, Melamed J, Handratta VD, Njar VC, Brodie AM, Yu LR, Veenstra TD, Chen H, Qiu Y. Guo Z, et al. Among authors: handratta vd. Cancer Cell. 2006 Oct;10(4):309-19. doi: 10.1016/j.ccr.2006.08.021. Cancer Cell. 2006. PMID: 17045208 Free article.

2

Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model.

Jelovac D, Macedo L, Goloubeva OG, Handratta V, Brodie AM. Jelovac D, et al. Cancer Res. 2005 Jun 15;65(12):5439-44. doi: 10.1158/0008-5472.CAN-04-2782. Cancer Res. 2005. PMID: 15958593

3

Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.

Handratta VD, Jelovac D, Long BJ, Kataria R, Nnane IP, Njar VC, Brodie AM. Handratta VD, et al. J Steroid Biochem Mol Biol. 2004 Oct;92(3):155-65. doi: 10.1016/j.jsbmb.2004.07.006. J Steroid Biochem Mol Biol. 2004. PMID: 15555909

4

Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.

Handratta VD, Vasaitis TS, Njar VC, Gediya LK, Kataria R, Chopra P, Newman D Jr, Farquhar R, Guo Z, Qiu Y, Brodie AM. Handratta VD, et al. J Med Chem. 2005 Apr 21;48(8):2972-84. doi: 10.1021/jm040202w. J Med Chem. 2005. PMID: 15828836

5

Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.

Patel JB, Khandelwal A, Chopra P, Handratta VD, Njar VC. Patel JB, et al. Among authors: handratta vd. Cancer Chemother Pharmacol. 2007 Nov;60(6):899-905. doi: 10.1007/s00280-007-0438-3. Epub 2007 Mar 8. Cancer Chemother Pharmacol. 2007. PMID: 17345084

6

Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.

Patel JB, Huynh CK, Handratta VD, Gediya LK, Brodie AM, Goloubeva OG, Clement OO, Nanne IP, Soprano DR, Njar VC. Patel JB, et al. Among authors: handratta vd. J Med Chem. 2004 Dec 30;47(27):6716-29. doi: 10.1021/jm0401457. J Med Chem. 2004. PMID: 15615521

7

Effects of exemestane and tamoxifen in a postmenopausal breast cancer model.

Jelovac D, Macedo L, Handratta V, Long BJ, Goloubeva OG, Ingle JN, Brodie AM. Jelovac D, et al. Clin Cancer Res. 2004 Nov 1;10(21):7375-81. doi: 10.1158/1078-0432.CCR-04-0565. Clin Cancer Res. 2004. PMID: 15534114

8

Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model.

Long BJ, Jelovac D, Handratta V, Thiantanawat A, MacPherson N, Ragaz J, Goloubeva OG, Brodie AM. Long BJ, et al. J Natl Cancer Inst. 2004 Mar 17;96(6):456-65. doi: 10.1093/jnci/djh076. J Natl Cancer Inst. 2004. PMID: 15026471

9

Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.

Clement OO, Freeman CM, Hartmann RW, Handratta VD, Vasaitis TS, Brodie AM, Njar VC. Clement OO, et al. Among authors: handratta vd. J Med Chem. 2003 Jun 5;46(12):2345-51. doi: 10.1021/jm020576u. J Med Chem. 2003. PMID: 12773039

10

Novel P450(17alpha) inhibitors: 17-(2'-oxazolyl)- and 17-(2'-thiazolyl)-androstene derivatives.

Zhu N, Ling Y, Lei X, Handratta V, Brodie AM. Zhu N, et al. Steroids. 2003 Sep;68(7-8):603-11. doi: 10.1016/s0039-128x(03)00082-5. Steroids. 2003. PMID: 12957665

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