Krishnegowda G - Search Results

1

Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes.

Lahoti TS, John K, Hughes JM, Kusnadi A, Murray IA, Krishnegowda G, Amin S, Perdew GH. Lahoti TS, et al. Among authors: krishnegowda g. Ann Rheum Dis. 2013 Oct;72(10):1708-16. doi: 10.1136/annrheumdis-2012-202639. Epub 2013 Jan 24. Ann Rheum Dis. 2013. PMID: 23349129 Free PMC article.

2

Ah receptor antagonism represses head and neck tumor cell aggressive phenotype.

DiNatale BC, Smith K, John K, Krishnegowda G, Amin SG, Perdew GH. DiNatale BC, et al. Among authors: krishnegowda g. Mol Cancer Res. 2012 Oct;10(10):1369-79. doi: 10.1158/1541-7786.MCR-12-0216. Epub 2012 Aug 21. Mol Cancer Res. 2012. PMID: 22912337 Free PMC article.

3

Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposure.

Narayanan GA, Murray IA, Krishnegowda G, Amin S, Perdew GH. Narayanan GA, et al. Among authors: krishnegowda g. J Pharmacol Exp Ther. 2012 Aug;342(2):345-55. doi: 10.1124/jpet.112.193482. Epub 2012 May 2. J Pharmacol Exp Ther. 2012. PMID: 22553215 Free PMC article.

4

Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases.

Gowda AS, Krishnegowda G, Suo Z, Amin S, Spratt TE. Gowda AS, et al. Among authors: krishnegowda g. Chem Res Toxicol. 2012 Jun 18;25(6):1195-202. doi: 10.1021/tx200483g. Epub 2012 May 1. Chem Res Toxicol. 2012. PMID: 22533615

5

Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation.

Doi K, Li R, Sung SS, Wu H, Liu Y, Manieri W, Krishnegowda G, Awwad A, Dewey A, Liu X, Amin S, Cheng C, Qin Y, Schonbrunn E, Daughdrill G, Loughran TP Jr, Sebti S, Wang HG. Doi K, et al. Among authors: krishnegowda g. J Biol Chem. 2012 Mar 23;287(13):10224-10235. doi: 10.1074/jbc.M111.334532. Epub 2012 Feb 6. J Biol Chem. 2012. PMID: 22311987 Free PMC article.

6

Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents.

Crowell SR, Amin SG, Anderson KA, Krishnegowda G, Sharma AK, Soelberg JJ, Williams DE, Corley RA. Crowell SR, et al. Among authors: krishnegowda g. Toxicol Appl Pharmacol. 2011 Dec 15;257(3):365-76. doi: 10.1016/j.taap.2011.09.020. Epub 2011 Sep 29. Toxicol Appl Pharmacol. 2011. PMID: 22001385 Free PMC article.

7

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway.

Krishnegowda G, Prakasha Gowda AS, Tagaram HR, Carroll KF, Irby RB, Sharma AK, Amin S. Krishnegowda G, et al. Bioorg Med Chem. 2011 Oct 15;19(20):6006-14. doi: 10.1016/j.bmc.2011.08.044. Epub 2011 Aug 26. Bioorg Med Chem. 2011. PMID: 21920762 Free PMC article.

8

Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides.

Krishnegowda G, Sharma AK, Krzeminski J, Gowda AS, Lin JM, Desai D, Spratt TE, Amin S. Krishnegowda G, et al. Chem Res Toxicol. 2011 Jun 20;24(6):960-7. doi: 10.1021/tx200127j. Epub 2011 May 5. Chem Res Toxicol. 2011. PMID: 21524094 Free PMC article.

9

Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1.

Zhu J, Krishnegowda G, Li G, Gowda DC. Zhu J, et al. Among authors: krishnegowda g. Exp Parasitol. 2011 Jul;128(3):205-11. doi: 10.1016/j.exppara.2011.03.010. Epub 2011 Mar 31. Exp Parasitol. 2011. PMID: 21439957 Free PMC article.

10

Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties.

Murray IA, Krishnegowda G, DiNatale BC, Flaveny C, Chiaro C, Lin JM, Sharma AK, Amin S, Perdew GH. Murray IA, et al. Among authors: krishnegowda g. Chem Res Toxicol. 2010 May 17;23(5):955-66. doi: 10.1021/tx100045h. Chem Res Toxicol. 2010. PMID: 20423157 Free PMC article.

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