Onda M - Search Results

1

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors.

Gubbels JA, Belisle J, Onda M, Rancourt C, Migneault M, Ho M, Bera TK, Connor J, Sathyanarayana BK, Lee B, Pastan I, Patankar MS. Gubbels JA, et al. Among authors: onda m. Mol Cancer. 2006 Oct 26;5(1):50. doi: 10.1186/1476-4598-5-50. Mol Cancer. 2006. PMID: 17067392 Free PMC article.

2

A bivalent disulfide-stabilized Fv with improved antigen binding to erbB2.

Bera TK, Onda M, Brinkmann U, Pastan I. Bera TK, et al. Among authors: onda m. J Mol Biol. 1998 Aug 21;281(3):475-83. doi: 10.1006/jmbi.1998.1948. J Mol Biol. 1998. PMID: 9698563

3

Reduction of the nonspecific animal toxicity of anti-Tac(Fv)-PE38 by mutations in the framework regions of the Fv which lower the isoelectric point.

Onda M, Kreitman RJ, Vasmatzis G, Lee B, Pastan I. Onda M, et al. J Immunol. 1999 Dec 1;163(11):6072-7. J Immunol. 1999. PMID: 10570296

4

Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.

Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I. Onda M, et al. Cancer Res. 2001 Jul 1;61(13):5070-7. Cancer Res. 2001. PMID: 11431343

5

Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments.

Nagata S, Onda M, Numata Y, Santora K, Beers R, Kreitman RJ, Pastan I. Nagata S, et al. Among authors: onda m. Clin Cancer Res. 2002 Jul;8(7):2345-55. Clin Cancer Res. 2002. PMID: 12114439

6

Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin.

Fan D, Yano S, Shinohara H, Solorzano C, Van Arsdall M, Bucana CD, Pathak S, Kruzel E, Herbst RS, Onn A, Roach JS, Onda M, Wang QC, Pastan I, Fidler IJ. Fan D, et al. Among authors: onda m. Mol Cancer Ther. 2002 Jun;1(8):595-600. Mol Cancer Ther. 2002. PMID: 12479219

7

Mutants of immunotoxin anti-Tac(dsFv)-PE38 with variable number of lysine residues as candidates for site-specific chemical modification. 1. Properties of mutant molecules.

Onda M, Vincent JJ, Lee B, Pastan I. Onda M, et al. Bioconjug Chem. 2003 Mar-Apr;14(2):480-7. doi: 10.1021/bc020069r. Bioconjug Chem. 2003. PMID: 12643760

8

High-density functional display of proteins on bacteriophage lambda.

Gupta A, Onda M, Pastan I, Adhya S, Chaudhary VK. Gupta A, et al. Among authors: onda m. J Mol Biol. 2003 Nov 21;334(2):241-54. doi: 10.1016/j.jmb.2003.09.033. J Mol Biol. 2003. PMID: 14607116

9

In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma.

Onda M, Wang QC, Guo HF, Cheung NK, Pastan I. Onda M, et al. Cancer Res. 2004 Feb 15;64(4):1419-24. doi: 10.1158/0008-5472.can-03-0570. Cancer Res. 2004. PMID: 14973056

10

Rapid grouping of monoclonal antibodies based on their topographical epitopes by a label-free competitive immunoassay.

Nagata S, Numata Y, Onda M, Ise T, Hahn Y, Lee B, Pastan I. Nagata S, et al. Among authors: onda m. J Immunol Methods. 2004 Sep;292(1-2):141-55. doi: 10.1016/j.jim.2004.06.009. J Immunol Methods. 2004. PMID: 15350519

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