Pop C - Search Results

1

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.

Feeney B, Pop C, Swartz P, Mattos C, Clark AC. Feeney B, et al. Among authors: pop c. Biochemistry. 2006 Nov 7;45(44):13249-63. doi: 10.1021/bi0611964. Biochemistry. 2006. PMID: 17073446 Free PMC article.

2

An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3.

Bose K, Pop C, Feeney B, Clark AC. Bose K, et al. Among authors: pop c. Biochemistry. 2003 Oct 28;42(42):12298-310. doi: 10.1021/bi034998x. Biochemistry. 2003. PMID: 14567691 Free PMC article.

3

Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.

Pop C, Feeney B, Tripathy A, Clark AC. Pop C, et al. Biochemistry. 2003 Oct 28;42(42):12311-20. doi: 10.1021/bi034999p. Biochemistry. 2003. PMID: 14567692 Free PMC article.

4

Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3.

Feeney B, Pop C, Tripathy A, Clark AC. Feeney B, et al. Among authors: pop c. Biochem J. 2004 Dec 15;384(Pt 3):515-25. doi: 10.1042/BJ20040693. Biochem J. 2004. PMID: 15312047 Free PMC article.

5

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.

Walters J, Pop C, Scott FL, Drag M, Swartz P, Mattos C, Salvesen GS, Clark AC. Walters J, et al. Among authors: pop c. Biochem J. 2009 Dec 10;424(3):335-45. doi: 10.1042/BJ20090825. Biochem J. 2009. PMID: 19788411 Free PMC article.

6

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

Pop C, Chen YR, Smith B, Bose K, Bobay B, Tripathy A, Franzen S, Clark AC. Pop C, et al. Biochemistry. 2001 Nov 27;40(47):14224-35. doi: 10.1021/bi011037e. Biochemistry. 2001. PMID: 11714276

7

Role of proteolysis in caspase-8 activation and stabilization.

Pop C, Fitzgerald P, Green DR, Salvesen GS. Pop C, et al. Biochemistry. 2007 Apr 10;46(14):4398-407. doi: 10.1021/bi602623b. Epub 2007 Mar 20. Biochemistry. 2007. PMID: 17371051

8

Activation and specificity of human caspase-10.

Wachmann K, Pop C, van Raam BJ, Drag M, Mace PD, Snipas SJ, Zmasek C, Schwarzenbacher R, Salvesen GS, Riedl SJ. Wachmann K, et al. Among authors: pop c. Biochemistry. 2010 Sep 28;49(38):8307-15. doi: 10.1021/bi100968m. Biochemistry. 2010. PMID: 20795673 Free PMC article.

9

Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.

Denault JB, Eckelman BP, Shin H, Pop C, Salvesen GS. Denault JB, et al. Among authors: pop c. Biochem J. 2007 Jul 1;405(1):11-9. doi: 10.1042/BJ20070288. Biochem J. 2007. PMID: 17437405 Free PMC article.

10

Caspase assays: identifying caspase activity and substrates in vitro and in vivo.

Pop C, Salvesen GS, Scott FL. Pop C, et al. Methods Enzymol. 2008;446:351-67. doi: 10.1016/S0076-6879(08)01621-2. Methods Enzymol. 2008. PMID: 18603133

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