Lightfoot AP - Search Results

1

Studies towards the identification of a new generation of atypical antipsychotic agents.

Garzya V, Forbes IT, Gribble AD, Hadley MS, Lightfoot AP, Payne AH, Smith AB, Douglas SE, Cooper DG, Stansfield IG, Meeson M, Dodds EE, Jones DN, Wood M, Reavill C, Scorer CA, Worby A, Riley G, Eddershaw P, Ioannou C, Donati D, Hagan JJ, Ratti EA. Garzya V, et al. Among authors: lightfoot ap. Bioorg Med Chem Lett. 2007 Jan 15;17(2):400-5. doi: 10.1016/j.bmcl.2006.10.036. Epub 2006 Oct 19. Bioorg Med Chem Lett. 2007. PMID: 17084080

2

SB-656104-A: a novel 5-HT(7) receptor antagonist with improved in vivo properties.

Forbes IT, Douglas S, Gribble AD, Ife RJ, Lightfoot AP, Garner AE, Riley GJ, Jeffrey P, Stevens AJ, Stean TO, Thomas DR. Forbes IT, et al. Among authors: lightfoot ap. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3341-4. doi: 10.1016/s0960-894x(02)00690-x. Bioorg Med Chem Lett. 2002. PMID: 12392747

3

Identification of a novel series of selective 5-HT7 receptor antagonists.

Forbes IT, Cooper DG, Dodds EK, Douglas SE, Gribble AD, Ife RJ, Lightfoot AP, Meeson M, Campbell LP, Coleman T, Riley GJ, Thomas DR. Forbes IT, et al. Among authors: lightfoot ap. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1055-8. doi: 10.1016/s0960-894x(03)00077-5. Bioorg Med Chem Lett. 2003. PMID: 12643910

4

1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists.

Micheli F, Bonanomi G, Blaney FE, Braggio S, Capelli AM, Checchia A, Curcuruto O, Damiani F, Fabio RD, Donati D, Gentile G, Gribble A, Hamprecht D, Tedesco G, Terreni S, Tarsi L, Lightfoot A, Stemp G, Macdonald G, Smith A, Pecoraro M, Petrone M, Perini O, Piner J, Rossi T, Worby A, Pilla M, Valerio E, Griffante C, Mugnaini M, Wood M, Scott C, Andreoli M, Lacroix L, Schwarz A, Gozzi A, Bifone A, Ashby CR Jr, Hagan JJ, Heidbreder C. Micheli F, et al. J Med Chem. 2007 Oct 18;50(21):5076-89. doi: 10.1021/jm0705612. Epub 2007 Sep 15. J Med Chem. 2007. PMID: 17867665

5

Identification of novel alpha7 nAChR positive allosteric modulators with the use of pharmacophore in silico screening methods.

Capelli AM, Castelletti L, Salvagno C, Oliosi B, Di Lenarda E, Virginio C, Lightfoot A, Kew JN, Teague S. Capelli AM, et al. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4561-5. doi: 10.1016/j.bmcl.2010.06.014. Epub 2010 Jun 8. Bioorg Med Chem Lett. 2010. PMID: 20591663

6

Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.

Lightfoot AP, Kew JN, Skidmore J. Lightfoot AP, et al. Prog Med Chem. 2008;46:131-71. doi: 10.1016/S0079-6468(07)00003-3. Prog Med Chem. 2008. PMID: 18381125 Review. No abstract available.

7

A stereoselective synthesis of 1,6-diphenyl-1,3,5-hexatrienes utilising 4,4,6-trimethyl-2-vinyl-1,3,2-dioxaborinane as a two-carbon alkenyl building block.

Lightfoot AP, Twiddle SJ, Whiting A. Lightfoot AP, et al. Org Biomol Chem. 2005 Sep 7;3(17):3167-72. doi: 10.1039/b507900d. Epub 2005 Jul 20. Org Biomol Chem. 2005. PMID: 16106297

8

A novel, efficient, diastereo- and enantioselective Mukaiyama aldol-based synthesis of a vinyl cyclopentanone core derivative of viridenomycin.

Batsanov AS, Knowles JP, Lightfoot AP, Maw G, Thirsk CE, Twiddle SJ, Whiting A. Batsanov AS, et al. Among authors: lightfoot ap. Org Lett. 2007 Dec 20;9(26):5565-8. doi: 10.1021/ol7025262. Epub 2007 Nov 17. Org Lett. 2007. PMID: 18020354

9

A novel scandium ortho-methoxynitrosobenzene-dimer complex: mechanistic implications for the nitroso-Diels-Alder reaction.

Lightfoot AP, Pritchard RG, Wan H, Warren JE, Whiting A. Lightfoot AP, et al. Chem Commun (Camb). 2002 Sep 21;(18):2072-3. doi: 10.1039/b206366b. Chem Commun (Camb). 2002. PMID: 12357784

10

Direct evidence for a ruthenium(IV) oxo complex-mediated oxidation of a hydroxamic acid in the presence of phosphine oxide donors.

Flower KR, Lightfoot AP, Wan H, Whiting A. Flower KR, et al. Among authors: lightfoot ap. Chem Commun (Camb). 2001 Sep 21;(18):1812-3. doi: 10.1039/b106338n. Chem Commun (Camb). 2001. PMID: 12240327

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