Debiec-Rychter M - Search Results

1

Intestinal neurofibromatosis is a subtype of familial GIST and results from a dominant activating mutation in PDGFRA.

de Raedt T, Cools J, Debiec-Rychter M, Brems H, Mentens N, Sciot R, Himpens J, de Wever I, Schöffski P, Marynen P, Legius E. de Raedt T, et al. Gastroenterology. 2006 Dec;131(6):1907-12. doi: 10.1053/j.gastro.2006.07.002. Gastroenterology. 2006. PMID: 17087943

2

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

Dewaele B, Wasag B, Cools J, Sciot R, Prenen H, Vandenberghe P, Wozniak A, Schöffski P, Marynen P, Debiec-Rychter M. Dewaele B, et al. Clin Cancer Res. 2008 Sep 15;14(18):5749-58. doi: 10.1158/1078-0432.CCR-08-0533. Clin Cancer Res. 2008. PMID: 18794084

3

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants.

Debiec-Rychter M, Cools J, Dumez H, Sciot R, Stul M, Mentens N, Vranckx H, Wasag B, Prenen H, Roesel J, Hagemeijer A, Van Oosterom A, Marynen P. Debiec-Rychter M, et al. Gastroenterology. 2005 Feb;128(2):270-9. doi: 10.1053/j.gastro.2004.11.020. Gastroenterology. 2005. PMID: 15685537

4

Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients.

Maertens O, Prenen H, Debiec-Rychter M, Wozniak A, Sciot R, Pauwels P, De Wever I, Vermeesch JR, de Raedt T, De Paepe A, Speleman F, van Oosterom A, Messiaen L, Legius E. Maertens O, et al. Hum Mol Genet. 2006 Mar 15;15(6):1015-23. doi: 10.1093/hmg/ddl016. Epub 2006 Feb 6. Hum Mol Genet. 2006. PMID: 16461335

5

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.

Prenen H, Cools J, Mentens N, Folens C, Sciot R, Schöffski P, Van Oosterom A, Marynen P, Debiec-Rychter M. Prenen H, et al. Clin Cancer Res. 2006 Apr 15;12(8):2622-7. doi: 10.1158/1078-0432.CCR-05-2275. Clin Cancer Res. 2006. PMID: 16638875

6

GIST under imatinib therapy.

Sciot R, Debiec-Rychter M. Sciot R, et al. Semin Diagn Pathol. 2006 May;23(2):84-90. doi: 10.1053/j.semdp.2006.08.005. Semin Diagn Pathol. 2006. PMID: 17193821 Review.

7

Rectal gastrointestinal stromal tumors associated with a novel germline KIT mutation.

Woźniak A, Rutkowski P, Sciot R, Ruka W, Michej W, Debiec-Rychter M. Woźniak A, et al. Int J Cancer. 2008 May 1;122(9):2160-4. doi: 10.1002/ijc.23338. Int J Cancer. 2008. PMID: 18183595

8

Pathogenesis of vestibular schwannoma in ring chromosome 22.

Denayer E, Brems H, de Cock P, Evans GD, Van Calenbergh F, Bowers N, Sciot R, Debiec-Rychter M, Vermeesch JV, Fryns JP, Legius E. Denayer E, et al. BMC Med Genet. 2009 Sep 22;10:97. doi: 10.1186/1471-2350-10-97. BMC Med Genet. 2009. PMID: 19772601 Free PMC article.

9

Coactivated platelet-derived growth factor receptor {alpha} and epidermal growth factor receptor are potential therapeutic targets in intimal sarcoma.

Dewaele B, Floris G, Finalet-Ferreiro J, Fletcher CD, Coindre JM, Guillou L, Hogendoorn PC, Wozniak A, Vanspauwen V, Schöffski P, Marynen P, Vandenberghe P, Sciot R, Debiec-Rychter M. Dewaele B, et al. Cancer Res. 2010 Sep 15;70(18):7304-14. doi: 10.1158/0008-5472.CAN-10-1543. Epub 2010 Aug 4. Cancer Res. 2010. PMID: 20685895

10

Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies.

Wozniak A, Floris G, Debiec-Rychter M, Sciot R, Schöffski P. Wozniak A, et al. Cancer Invest. 2010 Oct;28(8):839-48. doi: 10.3109/07357907.2010.494322. Cancer Invest. 2010. PMID: 20690803 Review.

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