Mentens N - Search Results

1

Intestinal neurofibromatosis is a subtype of familial GIST and results from a dominant activating mutation in PDGFRA.

de Raedt T, Cools J, Debiec-Rychter M, Brems H, Mentens N, Sciot R, Himpens J, de Wever I, Schöffski P, Marynen P, Legius E. de Raedt T, et al. Among authors: mentens n. Gastroenterology. 2006 Dec;131(6):1907-12. doi: 10.1053/j.gastro.2006.07.002. Gastroenterology. 2006. PMID: 17087943

2

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants.

Debiec-Rychter M, Cools J, Dumez H, Sciot R, Stul M, Mentens N, Vranckx H, Wasag B, Prenen H, Roesel J, Hagemeijer A, Van Oosterom A, Marynen P. Debiec-Rychter M, et al. Among authors: mentens n. Gastroenterology. 2005 Feb;128(2):270-9. doi: 10.1053/j.gastro.2004.11.020. Gastroenterology. 2005. PMID: 15685537

3

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.

Prenen H, Cools J, Mentens N, Folens C, Sciot R, Schöffski P, Van Oosterom A, Marynen P, Debiec-Rychter M. Prenen H, et al. Among authors: mentens n. Clin Cancer Res. 2006 Apr 15;12(8):2622-7. doi: 10.1158/1078-0432.CCR-05-2275. Clin Cancer Res. 2006. PMID: 16638875

4

Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.

Lierman E, Folens C, Stover EH, Mentens N, Van Miegroet H, Scheers W, Boogaerts M, Vandenberghe P, Marynen P, Cools J. Lierman E, et al. Among authors: mentens n. Blood. 2006 Aug 15;108(4):1374-6. doi: 10.1182/blood-2006-02-004457. Epub 2006 Apr 27. Blood. 2006. PMID: 16645167 Free PMC article.

5

The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.

Lierman E, Lahortiga I, Van Miegroet H, Mentens N, Marynen P, Cools J. Lierman E, et al. Among authors: mentens n. Haematologica. 2007 Jan;92(1):27-34. doi: 10.3324/haematol.10692. Haematologica. 2007. PMID: 17229632 Free article.

6

Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion.

Lahortiga I, Akin C, Cools J, Wilson TM, Mentens N, Arthur DC, Maric I, Noel P, Kocabas C, Marynen P, Lessin LS, Wlodarska I, Robyn J, Metcalfe DD. Lahortiga I, et al. Among authors: mentens n. Haematologica. 2008 Jan;93(1):49-56. doi: 10.3324/haematol.11836. Haematologica. 2008. PMID: 18166785 Free article.

7

Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13).

Cools J, Mentens N, Odero MD, Peeters P, Wlodarska I, Delforge M, Hagemeijer A, Marynen P. Cools J, et al. Among authors: mentens n. Blood. 2002 Mar 1;99(5):1776-84. doi: 10.1182/blood.v99.5.1776. Blood. 2002. PMID: 11861295 Free article.

8

A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif.

Cools J, Mentens N, Marynen P. Cools J, et al. Among authors: mentens n. FEBS Lett. 2001 Mar 16;492(3):204-9. doi: 10.1016/s0014-5793(01)02240-2. FEBS Lett. 2001. PMID: 11257495 Free article.

9

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, Vandenberghe P, Odero MD, Marynen P, Cools J. De Keersmaecker K, et al. Among authors: mentens n. Haematologica. 2008 Apr;93(4):533-42. doi: 10.3324/haematol.11894. Epub 2008 Mar 5. Haematologica. 2008. PMID: 18322257 Free article.

10

MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context.

Kleppe M, Mentens N, Tousseyn T, Wlodarska I, Cools J. Kleppe M, et al. Among authors: mentens n. Haematologica. 2011 May;96(5):779-83. doi: 10.3324/haematol.2010.035931. Epub 2010 Dec 29. Haematologica. 2011. PMID: 21193420 Free PMC article.

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