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Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.
Mongillo M, McSorley T, Evellin S, Sood A, Lissandron V, Terrin A, Huston E, Hannawacker A, Lohse MJ, Pozzan T, Houslay MD, Zaccolo M. Mongillo M, et al. Among authors: houslay md. Circ Res. 2004 Jul 9;95(1):67-75. doi: 10.1161/01.RES.0000134629.84732.11. Epub 2004 Jun 3. Circ Res. 2004. PMID: 15178638
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.
Lynch MJ, Baillie GS, Mohamed A, Li X, Maisonneuve C, Klussmann E, van Heeke G, Houslay MD. Lynch MJ, et al. Among authors: houslay md. J Biol Chem. 2005 Sep 30;280(39):33178-89. doi: 10.1074/jbc.M414316200. Epub 2005 Jul 19. J Biol Chem. 2005. PMID: 16030021 Free article.
413 results