Senisterra GA - Search Results

1

Screening for ligands using a generic and high-throughput light-scattering-based assay.

Senisterra GA, Markin E, Yamazaki K, Hui R, Vedadi M, Awrey DE. Senisterra GA, et al. J Biomol Screen. 2006 Dec;11(8):940-8. doi: 10.1177/1087057106294699. Epub 2006 Nov 7. J Biomol Screen. 2006. PMID: 17092916

2

Application of high-throughput isothermal denaturation to assess protein stability and screen for ligands.

Senisterra GA, Soo Hong B, Park HW, Vedadi M. Senisterra GA, et al. J Biomol Screen. 2008 Jun;13(5):337-42. doi: 10.1177/1087057108317825. Epub 2008 Apr 30. J Biomol Screen. 2008. PMID: 18448703

3

Assessing the stability of membrane proteins to detect ligand binding using differential static light scattering.

Senisterra GA, Ghanei H, Khutoreskaya G, Dobrovetsky E, Edwards AM, Privé GG, Vedadi M. Senisterra GA, et al. J Biomol Screen. 2010 Mar;15(3):314-20. doi: 10.1177/1087057109357117. Epub 2010 Feb 11. J Biomol Screen. 2010. PMID: 20150591

4

Biophysical characterization of recombinant proteins: a key to higher structural genomics success.

Vedadi M, Arrowsmith CH, Allali-Hassani A, Senisterra G, Wasney GA. Vedadi M, et al. Among authors: senisterra g. J Struct Biol. 2010 Oct;172(1):107-19. doi: 10.1016/j.jsb.2010.05.005. Epub 2010 May 11. J Struct Biol. 2010. PMID: 20466062 Free PMC article. Review.

5

Thermal denaturation assays in chemical biology.

Senisterra G, Chau I, Vedadi M. Senisterra G, et al. Assay Drug Dev Technol. 2012 Apr;10(2):128-36. doi: 10.1089/adt.2011.0390. Epub 2011 Nov 8. Assay Drug Dev Technol. 2012. PMID: 22066913 Review.

6

Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins.

Wigle TJ, Herold JM, Senisterra GA, Vedadi M, Kireev DB, Arrowsmith CH, Frye SV, Janzen WP. Wigle TJ, et al. Among authors: senisterra ga. J Biomol Screen. 2010 Jan;15(1):62-71. doi: 10.1177/1087057109352902. Epub 2009 Dec 11. J Biomol Screen. 2010. PMID: 20008125

7

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.

Wernimont AK, Artz JD, Finerty P Jr, Lin YH, Amani M, Allali-Hassani A, Senisterra G, Vedadi M, Tempel W, Mackenzie F, Chau I, Lourido S, Sibley LD, Hui R. Wernimont AK, et al. Nat Struct Mol Biol. 2010 May;17(5):596-601. doi: 10.1038/nsmb.1795. Epub 2010 May 2. Nat Struct Mol Biol. 2010. PMID: 20436473 Free PMC article.

8

Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.

Hong BS, Senisterra G, Rabeh WM, Vedadi M, Leonardi R, Zhang YM, Rock CO, Jackowski S, Park HW. Hong BS, et al. J Biol Chem. 2007 Sep 21;282(38):27984-93. doi: 10.1074/jbc.M701915200. Epub 2007 Jul 13. J Biol Chem. 2007. PMID: 17631502 Free article.

9

The Cryptosporidium parvum kinome.

Artz JD, Wernimont AK, Allali-Hassani A, Zhao Y, Amani M, Lin YH, Senisterra G, Wasney GA, Fedorov O, King O, Roos A, Lunin VV, Qiu W, Finerty P Jr, Hutchinson A, Chau I, von Delft F, MacKenzie F, Lew J, Kozieradzki I, Vedadi M, Schapira M, Zhang C, Shokat K, Heightman T, Hui R. Artz JD, et al. Among authors: senisterra g. BMC Genomics. 2011 Sep 30;12:478. doi: 10.1186/1471-2164-12-478. BMC Genomics. 2011. PMID: 21962082 Free PMC article.

10

Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.

Pizarro JC, Hills T, Senisterra G, Wernimont AK, Mackenzie C, Norcross NR, Ferguson MA, Wyatt PG, Gilbert IH, Hui R. Pizarro JC, et al. PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2492. doi: 10.1371/journal.pntd.0002492. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24147171 Free PMC article.

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