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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Among authors: deng x. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.
A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis.
Ruvolo PP, Deng X, Carr BK, May WS. Ruvolo PP, et al. Among authors: deng x. J Biol Chem. 1998 Sep 25;273(39):25436-42. doi: 10.1074/jbc.273.39.25436. J Biol Chem. 1998. PMID: 9738012 Free article.
Phosphorylation of Bcl2 at serine 70 may result from activation of a classic protein kinase C (PKC) isoform and is required for functional suppression of apoptosis by Bcl2 in murine growth factor-dependent cell lines (Ito, T., Deng, X., Carr, B., and May, W. S. (199 …
Phosphorylation of Bcl2 at serine 70 may result from activation of a classic protein kinase C (PKC) isoform and is required for functional s …
Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A.
Ruvolo PP, Deng X, Ito T, Carr BK, May WS. Ruvolo PP, et al. Among authors: deng x. J Biol Chem. 1999 Jul 16;274(29):20296-300. doi: 10.1074/jbc.274.29.20296. J Biol Chem. 1999. PMID: 10400650 Free article.
We have recently shown that Bcl2 phosphorylation is a dynamic process that involves the protein kinase C alpha and protein phosphatase 2A (PP2A) (Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) J. Biol. Chem. 273, 25436-25442; and Deng, X., …
We have recently shown that Bcl2 phosphorylation is a dynamic process that involves the protein kinase C alpha and protein phosphatase 2A (P …
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