Patenaude A - Search Results

1

Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells.

Deschesnes RG, Patenaude A, Rousseau JL, Fortin JS, Ricard C, Côté MF, Huot J, C-Gaudreault R, Petitclerc E. Deschesnes RG, et al. Among authors: patenaude a. J Pharmacol Exp Ther. 2007 Feb;320(2):853-64. doi: 10.1124/jpet.106.110957. Epub 2006 Nov 10. J Pharmacol Exp Ther. 2007. PMID: 17099073

2

ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas.

Fortin J, Patenaude A, Deschesnes RG, Côté MF, Petitclerc E, C-Gaudreault R. Fortin J, et al. Among authors: patenaude a. J Pharm Pharm Sci. 2010;13(2):175-90. doi: 10.18433/j31g6c. J Pharm Pharm Sci. 2010. PMID: 20816004 Free article.

3

New soft alkylating agents with enhanced cytotoxicity against cancer cells resistant to chemotherapeutics and hypoxia.

Patenaude A, Deschesnes RG, Rousseau JL, Petitclerc E, Lacroix J, Côté MF, C-Gaudreault R. Patenaude A, et al. Cancer Res. 2007 Mar 1;67(5):2306-16. doi: 10.1158/0008-5472.CAN-06-3824. Cancer Res. 2007. PMID: 17332362

4

Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.

Fortin JS, Lacroix J, Desjardins M, Patenaude A, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Among authors: patenaude a. Bioorg Med Chem. 2007 Jul 1;15(13):4456-69. doi: 10.1016/j.bmc.2007.04.028. Epub 2007 Apr 22. Bioorg Med Chem. 2007. PMID: 17498960

5

Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation.

Fortin JS, Côté MF, Lacroix J, Patenaude A, Petitclerc E, C-Gaudreault R. Fortin JS, et al. Among authors: patenaude a. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3526-31. doi: 10.1016/j.bmcl.2008.05.028. Epub 2008 May 10. Bioorg Med Chem Lett. 2008. PMID: 18502639

6

Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation.

Patenaude A, Fortin JS, Deschenes R, Côté MF, Lacroix J, C-Gaudreault R, Petitclerc E. Patenaude A, et al. Can J Physiol Pharmacol. 2010 Nov;88(11):1102-14. doi: 10.1139/y10-084. Can J Physiol Pharmacol. 2010. PMID: 21076498

7

N-Phenyl-N'-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: role of omega-hydroxyl group in the covalent binding to beta-tubulin.

Fortin S, Moreau E, Patenaude A, Desjardins M, Lacroix J, Rousseau JL, C-Gaudreault R. Fortin S, et al. Among authors: patenaude a. Bioorg Med Chem. 2007 Feb 1;15(3):1430-8. doi: 10.1016/j.bmc.2006.11.005. Epub 2006 Nov 10. Bioorg Med Chem. 2007. PMID: 17118664 Free article.

8

N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety?

Fortin S, Moreau E, Lacroix J, Teulade JC, Patenaude A, C-Gaudreault R. Fortin S, et al. Among authors: patenaude a. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2000-4. doi: 10.1016/j.bmcl.2007.01.023. Epub 2007 Jan 19. Bioorg Med Chem Lett. 2007. PMID: 17291753 Free article.

9

Membrane composition modulates the interaction between a new class of antineoplastic agents deriving from aromatic 2-chloroethylureas and lipid bilayers: a solid-state NMR study.

Cronier F, Patenaude A, C-Gaudreault R, Auger M. Cronier F, et al. Among authors: patenaude a. Chem Phys Lipids. 2007 Apr;146(2):125-35. doi: 10.1016/j.chemphyslip.2007.01.002. Epub 2007 Jan 18. Chem Phys Lipids. 2007. PMID: 17291469

10

N-Phenyl-N'-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: role of carbonyl groups in the covalent binding to the colchicine-binding site.

Moreau E, Fortin S, Lacroix J, Patenaude A, Rousseau JL, C-Gaudreault R. Moreau E, et al. Among authors: patenaude a. Bioorg Med Chem. 2008 Feb 1;16(3):1206-17. doi: 10.1016/j.bmc.2007.10.078. Epub 2007 Nov 12. Bioorg Med Chem. 2008. PMID: 17998163 Free article.

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