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Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards.
Tweats DJ, Blakey D, Heflich RH, Jacobs A, Jacobsen SD, Morita T, Nohmi T, O'Donovan MR, Sasaki YF, Sofuni T, Tice R; IWGT Working Group. Tweats DJ, et al. Mutat Res. 2007 Feb 3;627(1):78-91. doi: 10.1016/j.mrgentox.2006.10.005. Epub 2006 Nov 20. Mutat Res. 2007. PMID: 17116417
Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test.
Tweats DJ, Blakey D, Heflich RH, Jacobs A, Jacobsen SD, Morita T, Nohmi T, O'Donovan MR, Sasaki YF, Sofuni T, Tice R; IWGT Working Group. Tweats DJ, et al. Mutat Res. 2007 Feb 3;627(1):92-105. doi: 10.1016/j.mrgentox.2006.10.006. Epub 2006 Nov 20. Mutat Res. 2007. PMID: 17113817 Free PMC article. Review.
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Kirkland D, et al. Mutat Res. 2007 Mar 30;628(1):31-55. doi: 10.1016/j.mrgentox.2006.11.008. Epub 2007 Jan 13. Mutat Res. 2007. PMID: 17293159
Strategy for genotoxicity testing and stratification of genotoxicity test results--report on initial activities of the IWGT Expert Group.
Müller L, Blakey D, Dearfield KL, Galloway S, Guzzie P, Hayashi M, Kasper P, Kirkland D, MacGregor JT, Parry JM, Schechtman L, Smith A, Tanaka N, Tweats D, Yamasaki H; IWGT Expert Group. Müller L, et al. Mutat Res. 2003 Oct 7;540(2):177-81. doi: 10.1016/j.mrgentox.2003.07.007. Mutat Res. 2003. PMID: 14550501 No abstract available.
Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.
Lynch AM, Eastmond D, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M, Tweats D. Lynch AM, et al. Mutat Res Genet Toxicol Environ Mutagen. 2019 Nov;847:403025. doi: 10.1016/j.mrgentox.2019.02.006. Epub 2019 Mar 2. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31699346 Review.
Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.
Kirkland DJ, Henderson L, Marzin D, Müller L, Parry JM, Speit G, Tweats DJ, Williams GM. Kirkland DJ, et al. Among authors: tweats dj. Mutat Res. 2005 Dec 30;588(2):88-105. doi: 10.1016/j.mrgentox.2005.09.006. Epub 2005 Dec 2. Mutat Res. 2005. PMID: 16326131 Review.
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method.
Billinton N, Hastwell PW, Beerens D, Birrell L, Ellis P, Maskell S, Webster TW, Windebank S, Woestenborghs F, Lynch AM, Scott AD, Tweats DJ, van Gompel J, Rees RW, Walmsley RM. Billinton N, et al. Among authors: tweats dj. Mutat Res. 2008 May 31;653(1-2):23-33. doi: 10.1016/j.mrgentox.2008.02.011. Epub 2008 Mar 27. Mutat Res. 2008. PMID: 18450500
Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.
Pacchierotti F, Masumura K, Eastmond DA, Elhajouji A, Froetschl R, Kirsch-Volders M, Lynch A, Schuler M, Tweats D, Marchetti F. Pacchierotti F, et al. Mutat Res Genet Toxicol Environ Mutagen. 2019 Dec;848:403023. doi: 10.1016/j.mrgentox.2019.02.004. Epub 2019 Mar 20. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31708072
45 results