Aleshin AE - Search Results

1

Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein.

Aoyagi M, Zhai D, Jin C, Aleshin AE, Stec B, Reed JC, Liddington RC. Aoyagi M, et al. Among authors: aleshin ae. Protein Sci. 2007 Jan;16(1):118-24. doi: 10.1110/ps.062454707. Epub 2006 Nov 22. Protein Sci. 2007. PMID: 17123957 Free PMC article.

2

Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention.

Cheltsov AV, Aoyagi M, Aleshin A, Yu EC, Gilliland T, Zhai D, Bobkov AA, Reed JC, Liddington RC, Abagyan R. Cheltsov AV, et al. J Med Chem. 2010 May 27;53(10):3899-906. doi: 10.1021/jm901446n. J Med Chem. 2010. PMID: 20441222 Free PMC article.

3

Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.

Aleshin AE, Shiryaev SA, Strongin AY, Liddington RC. Aleshin AE, et al. Protein Sci. 2007 May;16(5):795-806. doi: 10.1110/ps.072753207. Epub 2007 Mar 30. Protein Sci. 2007. PMID: 17400917 Free PMC article.

4

Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region.

Shiryaev SA, Aleshin AE, Ratnikov BI, Smith JW, Liddington RC, Strongin AY. Shiryaev SA, et al. Among authors: aleshin ae. Protein Expr Purif. 2007 Apr;52(2):334-9. doi: 10.1016/j.pep.2006.11.009. Epub 2006 Dec 1. Protein Expr Purif. 2007. PMID: 17189703 Free PMC article.

5

Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case.

Aleshin AE, Gramatikova S, Hura GL, Bobkov A, Strongin AY, Stec B, Tainer JA, Liddington RC, Smith JW. Aleshin AE, et al. Structure. 2009 Nov 11;17(11):1465-75. doi: 10.1016/j.str.2009.09.009. Structure. 2009. PMID: 19913481 Free PMC article.

6

Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC).

Aleshin AE, Schraufstatter IU, Stec B, Bankston LA, Liddington RC, DiScipio RG. Aleshin AE, et al. J Biol Chem. 2012 Mar 23;287(13):10210-10222. doi: 10.1074/jbc.M111.327809. Epub 2012 Jan 20. J Biol Chem. 2012. PMID: 22267737 Free PMC article.

7

Crystal structure of C5b-6 suggests structural basis for priming assembly of the membrane attack complex.

Aleshin AE, DiScipio RG, Stec B, Liddington RC. Aleshin AE, et al. J Biol Chem. 2012 Jun 1;287(23):19642-52. doi: 10.1074/jbc.M112.361121. Epub 2012 Apr 12. J Biol Chem. 2012. PMID: 22500023 Free PMC article.

8

Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis.

Shiryaev SA, Ratnikov BI, Aleshin AE, Kozlov IA, Nelson NA, Lebl M, Smith JW, Liddington RC, Strongin AY. Shiryaev SA, et al. Among authors: aleshin ae. J Virol. 2007 May;81(9):4501-9. doi: 10.1128/JVI.02719-06. Epub 2007 Feb 14. J Virol. 2007. PMID: 17301157 Free PMC article.

9

Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.

Radichev I, Shiryaev SA, Aleshin AE, Ratnikov BI, Smith JW, Liddington RC, Strongin AY. Radichev I, et al. Among authors: aleshin ae. J Gen Virol. 2008 Mar;89(Pt 3):636-641. doi: 10.1099/vir.0.83359-0. J Gen Virol. 2008. PMID: 18272753

10

The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase.

Chernov AV, Shiryaev SA, Aleshin AE, Ratnikov BI, Smith JW, Liddington RC, Strongin AY. Chernov AV, et al. Among authors: aleshin ae. J Biol Chem. 2008 Jun 20;283(25):17270-8. doi: 10.1074/jbc.M801719200. Epub 2008 Apr 28. J Biol Chem. 2008. PMID: 18442976 Free PMC article.

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