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Page 1
Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.
Giordano FA, Fehse B, Hotz-Wagenblatt A, Jonnakuty S, del Val C, Appelt JU, Nagy KZ, Kuehlcke K, Naundorf S, Zander AR, Zeller WJ, Ho AD, Fruehauf S, Laufs S. Giordano FA, et al. Among authors: kuehlcke k. Bone Marrow Transplant. 2006 Aug;38(3):229-35. doi: 10.1038/sj.bmt.1705424. Epub 2006 Jun 19. Bone Marrow Transplant. 2006. PMID: 16785865
Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.
Sundarasetty BS, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, Gerasch L, Figueiredo C, Blasczyk R, Ruggiero E, Fronza R, Schmidt M, von Kalle C, Rothe M, Ganser A, Koehl U, Stripecke R. Sundarasetty BS, et al. Among authors: kuehlcke k. J Transl Med. 2015 Jul 22;13:240. doi: 10.1186/s12967-015-0599-5. J Transl Med. 2015. PMID: 26198406 Free PMC article.
Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus.
van Lunzen J, Glaunsinger T, Stahmer I, von Baehr V, Baum C, Schilz A, Kuehlcke K, Naundorf S, Martinius H, Hermann F, Giroglou T, Newrzela S, Müller I, Brauer F, Brandenburg G, Alexandrov A, von Laer D. van Lunzen J, et al. Among authors: kuehlcke k. Mol Ther. 2007 May;15(5):1024-33. doi: 10.1038/mt.sj.6300124. Epub 2007 Mar 13. Mol Ther. 2007. PMID: 17356541 Free article. Clinical Trial.
Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma.
Sundarasetty BS, Chan L, Darling D, Giunti G, Farzaneh F, Schenck F, Naundorf S, Kuehlcke K, Ruggiero E, Schmidt M, von Kalle C, Rothe M, Hoon DS, Gerasch L, Figueiredo C, Koehl U, Blasczyk R, Gutzmer R, Stripecke R. Sundarasetty BS, et al. Among authors: kuehlcke k. Gene Ther. 2015 Sep;22(9):707-20. doi: 10.1038/gt.2015.43. Epub 2015 May 28. Gene Ther. 2015. PMID: 25965393 Free PMC article.
Transfer of Autologous Gene-modified T Cells in HIV-infected Patients with Advanced Immunodeficiency and Drug-resistant Virus.
Lunzen JV, Glaunsinger T, Stahmer I, Baehr VV, Baum C, Schilz A, Kuehlcke K, Naundorf S, Martinius H, Hermann F, Giroglou T, Newrzela S, Müller I, Brauer F, Brandenburg G, Alexandrov A, von Laer D. Lunzen JV, et al. Among authors: kuehlcke k. Mol Ther. 2007 May;15(5):1024-1033. doi: 10.1038/mt.sj.6300124. Epub 2016 Dec 7. Mol Ther. 2007. PMID: 28182893
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.
Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Modlich U, et al. Among authors: kuehlcke k. Blood. 2005 Jun 1;105(11):4235-46. doi: 10.1182/blood-2004-11-4535. Epub 2005 Feb 15. Blood. 2005. PMID: 15713797 Free article.
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