Watanabe T - Search Results

1

Efficient generation of 2'-deoxyuridin-5-yl at 5'-(G/C)AA(X)U(X)U-3' (X = Br, I) sequences in duplex DNA under UV-irradiation.

Watanabe T, Bando T, Xu Y, Sugiyama H. Watanabe T, et al. Nucleic Acids Symp Ser (Oxf). 2004;(48):19-20. doi: 10.1093/nass/48.1.19. Nucleic Acids Symp Ser (Oxf). 2004. PMID: 17150457

2

Efficient generation of 2'-deoxyuridin-5-yl at 5'-(G/C)AA(X)U(X)U-3' (X = Br, I) sequences in duplex DNA under UV irradiation.

Watanabe T, Bando T, Xu Y, Tashiro R, Sugiyama H. Watanabe T, et al. J Am Chem Soc. 2005 Jan 12;127(1):44-5. doi: 10.1021/ja0454743. J Am Chem Soc. 2005. PMID: 15631440

3

Photoreaction at 5'-(G/C)AA(Br)UT-3' sequence in duplex DNA: efficient generation of uracil-5-yl radical by charge transfer.

Watanabe T, Tashiro R, Sugiyama H. Watanabe T, et al. J Am Chem Soc. 2007 Jul 4;129(26):8163-8. doi: 10.1021/ja0692736. Epub 2007 Jun 12. J Am Chem Soc. 2007. PMID: 17564445

4

Development of pyrrole-imidazole polyamide for specific regulation of human aurora kinase-A and -B gene expression.

Takahashi T, Asami Y, Kitamura E, Suzuki T, Wang X, Igarashi J, Morohashi A, Shinojima Y, Kanou H, Saito K, Takasu T, Nagase H, Harada Y, Kuroda K, Watanabe T, Kumamoto S, Aoyama T, Matsumoto Y, Bando T, Sugiyama H, Yoshida-Noro C, Fukuda N, Hayashi N. Takahashi T, et al. Among authors: watanabe t. Chem Biol. 2008 Aug 25;15(8):829-41. doi: 10.1016/j.chembiol.2008.06.006. Chem Biol. 2008. PMID: 18721754

5

Development of a molecule-recognized promoter DNA sequence for inhibition of HER2 expression.

Suzuki T, Asami Y, Takahashi T, Wang X, Watanabe T, Bando T, Sugiyama H, Fukuda N, Nagase H. Suzuki T, et al. Among authors: watanabe t. J Antibiot (Tokyo). 2009 Jun;62(6):339-41. doi: 10.1038/ja.2009.35. Epub 2009 May 15. J Antibiot (Tokyo). 2009. PMID: 19444299 No abstract available.

6

Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide.

Wang X, Nagase H, Watanabe T, Nobusue H, Suzuki T, Asami Y, Shinojima Y, Kawashima H, Takagi K, Mishra R, Igarashi J, Kimura M, Takayama T, Fukuda N, Sugiyama H. Wang X, et al. Among authors: watanabe t. Cancer Sci. 2010 Mar;101(3):759-66. doi: 10.1111/j.1349-7006.2009.01435.x. Epub 2009 Nov 14. Cancer Sci. 2010. PMID: 20085585 Free PMC article.

7

Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter.

Matsuda H, Fukuda N, Ueno T, Katakawa M, Wang X, Watanabe T, Matsui S, Aoyama T, Saito K, Bando T, Matsumoto Y, Nagase H, Matsumoto K, Sugiyama H. Matsuda H, et al. Among authors: watanabe t. Kidney Int. 2011 Jan;79(1):46-56. doi: 10.1038/ki.2010.330. Epub 2010 Sep 22. Kidney Int. 2011. PMID: 20861821 Free article.

8

RNA binding properties of novel gene silencing pyrrole-imidazole polyamides.

Iguchi A, Fukuda N, Takahashi T, Watanabe T, Matsuda H, Nagase H, Bando T, Sugiyama H, Shimizu K. Iguchi A, et al. Among authors: watanabe t. Biol Pharm Bull. 2013;36(7):1152-8. doi: 10.1248/bpb.b13-00135. Epub 2013 Apr 30. Biol Pharm Bull. 2013. PMID: 23628892 Free article.

9

Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.

Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H. Hiraoka K, et al. Among authors: watanabe t. Nat Commun. 2015 Apr 27;6:6706. doi: 10.1038/ncomms7706. Nat Commun. 2015. PMID: 25913614 Free article.

10

Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model.

Igarashi J, Fukuda N, Inoue T, Nakai S, Saito K, Fujiwara K, Matsuda H, Ueno T, Matsumoto Y, Watanabe T, Nagase H, Bando T, Sugiyama H, Itoh T, Soma M. Igarashi J, et al. Among authors: watanabe t. PLoS One. 2015 May 4;10(5):e0125295. doi: 10.1371/journal.pone.0125295. eCollection 2015. PLoS One. 2015. PMID: 25938472 Free PMC article.

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