Stiborová M - Search Results

1

Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.

Dracínska H, Miksanová M, Svobodová M, Smrcek S, Frei E, Schmeiser HH, Stiborová M. Dracínska H, et al. Among authors: stiborova m. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:9-13. Neuro Endocrinol Lett. 2006. PMID: 17159769

2

Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

Stiborová M, Frei E, Sopko B, Sopková K, Marková V, Lanková M, Kumstýrová T, Wiessler M, Schmeiser HH. Stiborová M, et al. Carcinogenesis. 2003 Oct;24(10):1695-703. doi: 10.1093/carcin/bgg119. Epub 2003 Jul 17. Carcinogenesis. 2003. PMID: 12869422

3

Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans.

Stiborová M, Miksanová M, Smrcek S, Bieler CA, Breuer A, Klokow KA, Schmeiser HH, Frei E. Stiborová M, et al. Carcinogenesis. 2004 May;25(5):833-40. doi: 10.1093/carcin/bgh061. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729594

4

Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M. Miksanová M, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 May;17(5):663-71. doi: 10.1021/tx0499721. Chem Res Toxicol. 2004. PMID: 15144223

5

Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine.

Stiborová M, Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E. Stiborová M, et al. Int J Cancer. 2005 Sep 20;116(5):667-78. doi: 10.1002/ijc.21122. Int J Cancer. 2005. PMID: 15828049

6

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

7

Carcinogenic pollutants o-nitroanisole and o-anisidine are substrates and inducers of cytochromes P450.

Rýdlová H, Miksanová M, Ryslavá H, Stiborová M. Rýdlová H, et al. Among authors: stiborova m. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):441-7. doi: 10.5507/bp.2005.077. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005. PMID: 16601807

8

The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.

Stiborová M, Dracínská H, Hájková J, Kaderábková P, Frei E, Schmeiser HH, Soucek P, Phillips DH, Arlt VM. Stiborová M, et al. Drug Metab Dispos. 2006 Aug;34(8):1398-405. doi: 10.1124/dmd.106.009373. Epub 2006 May 19. Drug Metab Dispos. 2006. PMID: 16714372

9

Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes.

Kotrbová V, Aimová D, Brezinová A, Janouchová K, Poljaková J, Frei E, Stiborová M. Kotrbová V, et al. Among authors: stiborova m. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:18-22. Neuro Endocrinol Lett. 2006. PMID: 17159771

10

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser HH, Frei E. Stiborová M, et al. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:35-9. Neuro Endocrinol Lett. 2006. PMID: 17159775

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