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The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen-and progesterone-responsive endometrial cancer cell line.
J Mol Endocrinol. 2006 Dec;37(3):405-13. doi: 10.1677/jme.1.02057.
J Mol Endocrinol. 2006.
PMID: 17170081
Progestogenic effects of tibolone on human endometrial cancer cells.
Blok LJ, De Ruiter PE, Kühne EC, Hanekamp EE, Grootegoed JA, Smid-Koopman E, Gielen SC, De Gooyer ME, Kloosterboer HJ, Burger CW.
Blok LJ, et al. Among authors: kuhne ec.
J Clin Endocrinol Metab. 2003 May;88(5):2327-34. doi: 10.1210/jc.2002-021737.
J Clin Endocrinol Metab. 2003.
PMID: 12727992
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Loss of progesterone receptor may lead to an invasive phenotype in human endometrial cancer.
Hanekamp EE, Kühne EC, Smid-Koopman E, de Ruiter PE, Chadha-Ajwani S, Brinkmann AO, Burger CW, Grootegoed JA, Huikeshoven FJ, Blok LJ.
Hanekamp EE, et al. Among authors: kuhne ec.
Eur J Cancer. 2002 Nov;38 Suppl 6:S71-2. doi: 10.1016/s0959-8049(02)00294-0.
Eur J Cancer. 2002.
PMID: 12409083
No abstract available.
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