Amable L - Search Results

1

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.

Lawhorn BG, Boga SB, Wolkenberg SE, Colby DA, Gauss CM, Swingle MR, Amable L, Honkanen RE, Boger DL. Lawhorn BG, et al. Among authors: amable l. J Am Chem Soc. 2006 Dec 27;128(51):16720-32. doi: 10.1021/ja066477d. J Am Chem Soc. 2006. PMID: 17177422 Free PMC article.

2

Structure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and( beta12-beta13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors.

Swingle MR, Amable L, Lawhorn BG, Buck SB, Burke CP, Ratti P, Fischer KL, Boger DL, Honkanen RE. Swingle MR, et al. Among authors: amable l. J Pharmacol Exp Ther. 2009 Oct;331(1):45-53. doi: 10.1124/jpet.109.155630. Epub 2009 Jul 10. J Pharmacol Exp Ther. 2009. PMID: 19592665 Free PMC article.

3

Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).

Amable L, Grankvist N, Largen JW, Ortsäter H, Sjöholm Å, Honkanen RE. Amable L, et al. J Biol Chem. 2011 Nov 25;286(47):40413-22. doi: 10.1074/jbc.M111.244053. Epub 2011 Sep 15. J Biol Chem. 2011. PMID: 21921034 Free PMC article.

4

Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer.

Golden T, Aragon IV, Rutland B, Tucker JA, Shevde LA, Samant RS, Zhou G, Amable L, Skarra D, Honkanen RE. Golden T, et al. Among authors: amable l. Biochim Biophys Acta. 2008 Apr;1782(4):259-70. doi: 10.1016/j.bbadis.2008.01.004. Epub 2008 Jan 26. Biochim Biophys Acta. 2008. PMID: 18280813 Free PMC article.

5

Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.

Henesy MB, Britain AL, Zhu B, Amable L, Honkanen RE, Corbin JD, Francis SH, Rich TC. Henesy MB, et al. Among authors: amable l. PLoS One. 2012;7(8):e41711. doi: 10.1371/journal.pone.0041711. Epub 2012 Aug 2. PLoS One. 2012. PMID: 22876290 Free PMC article.

6

Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells.

Grankvist N, Amable L, Honkanen RE, Sjöholm A, Ortsäter H. Grankvist N, et al. Among authors: amable l. Diabetologia. 2012 Jul;55(7):2005-15. doi: 10.1007/s00125-012-2541-1. Epub 2012 Apr 12. Diabetologia. 2012. PMID: 22526606

7

GLI1 upregulates C-JUN through a specific 130-kDa isoform.

Amable L, Gavin E, Kudo K, Meng E, Rocconi RP, Shevde LA, Reed E. Amable L, et al. Int J Oncol. 2014 Mar;44(3):655-61. doi: 10.3892/ijo.2013.2222. Epub 2013 Dec 20. Int J Oncol. 2014. PMID: 24366538 Free PMC article.

8

Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair.

Kudo K, Gavin E, Das S, Amable L, Shevde LA, Reed E. Kudo K, et al. Among authors: amable l. Oncogene. 2012 Nov 1;31(44):4718-24. doi: 10.1038/onc.2011.610. Epub 2012 Jan 23. Oncogene. 2012. PMID: 22266871

9

Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug.

Amable L, Fain J, Gavin E, Reed E. Amable L, et al. Oncol Rep. 2014 Aug;32(2):469-74. doi: 10.3892/or.2014.3257. Epub 2014 Jun 12. Oncol Rep. 2014. PMID: 24926795 Free PMC article.

10

Family 18 chitinase-oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A.

Aronson NN Jr, Halloran BA, Alexyev MF, Amable L, Madura JD, Pasupulati L, Worth C, Van Roey P. Aronson NN Jr, et al. Among authors: amable l. Biochem J. 2003 Nov 15;376(Pt 1):87-95. doi: 10.1042/BJ20030273. Biochem J. 2003. PMID: 12932195 Free PMC article.

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