Oswald S - Search Results

1

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.

Grube M, Köck K, Oswald S, Draber K, Meissner K, Eckel L, Böhm M, Felix SB, Vogelgesang S, Jedlitschky G, Siegmund W, Warzok R, Kroemer HK. Grube M, et al. Among authors: oswald s. Clin Pharmacol Ther. 2006 Dec;80(6):607-20. doi: 10.1016/j.clpt.2006.09.010. Clin Pharmacol Ther. 2006. PMID: 17178262

2

A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1.

Oswald S, Scheuch E, Cascorbi I, Siegmund W. Oswald S, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 2;830(1):143-50. doi: 10.1016/j.jchromb.2005.10.034. Epub 2005 Nov 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16280261

3

Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.

Oswald S, Haenisch S, Fricke C, Sudhop T, Remmler C, Giessmann T, Jedlitschky G, Adam U, Dazert E, Warzok R, Wacke W, Cascorbi I, Kroemer HK, Weitschies W, von Bergmann K, Siegmund W. Oswald S, et al. Clin Pharmacol Ther. 2006 Mar;79(3):206-17. doi: 10.1016/j.clpt.2005.11.004. Epub 2006 Feb 7. Clin Pharmacol Ther. 2006. PMID: 16513445

4

Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats.

Oswald S, Westrup S, Grube M, Kroemer HK, Weitschies W, Siegmund W. Oswald S, et al. J Pharmacol Exp Ther. 2006 Sep;318(3):1293-9. doi: 10.1124/jpet.106.104018. Epub 2006 Jun 13. J Pharmacol Exp Ther. 2006. PMID: 16772539

5

Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins.

Oswald S, Giessmann T, Luetjohann D, Wegner D, Rosskopf D, Weitschies W, Siegmund W. Oswald S, et al. Clin Pharmacol Ther. 2006 Nov;80(5):477-85. doi: 10.1016/j.clpt.2006.07.006. Clin Pharmacol Ther. 2006. PMID: 17112804 Clinical Trial.

6

Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice.

Oswald S, Koll C, Siegmund W. Oswald S, et al. J Pharm Sci. 2007 Dec;96(12):3478-84. doi: 10.1002/jps.20996. J Pharm Sci. 2007. PMID: 17828742

7

Transporter-mediated uptake into cellular compartments.

Oswald S, Grube M, Siegmund W, Kroemer HK. Oswald S, et al. Xenobiotica. 2007 Oct-Nov;37(10-11):1171-95. doi: 10.1080/00498250701570251. Xenobiotica. 2007. PMID: 17968742 Review.

8

Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1.

Oswald S, König J, Lütjohann D, Giessmann T, Kroemer HK, Rimmbach C, Rosskopf D, Fromm MF, Siegmund W. Oswald S, et al. Pharmacogenet Genomics. 2008 Jul;18(7):559-68. doi: 10.1097/FPC.0b013e3282fe9a2c. Pharmacogenet Genomics. 2008. PMID: 18551036 Clinical Trial.

9

Oral absorption of propiverine solution and of the immediate and extended release dosage forms: influence of regioselective intestinal elimination.

May K, Giessmann T, Wegner D, Oertel R, Modess C, Oswald S, Braeter M, Siegmund W. May K, et al. Among authors: oswald s. Eur J Clin Pharmacol. 2008 Nov;64(11):1085-92. doi: 10.1007/s00228-008-0528-0. Epub 2008 Jul 15. Eur J Clin Pharmacol. 2008. PMID: 18626633 Clinical Trial.

10

Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.

Niessen J, Jedlitschky G, Grube M, Bien S, Schwertz H, Ohtsuki S, Kawakami H, Kamiie J, Oswald S, Starke K, Strobel U, Siegmund W, Rosskopf D, Greinacher A, Terasaki T, Kroemer HK. Niessen J, et al. Among authors: oswald s. Drug Metab Dispos. 2009 May;37(5):1129-37. doi: 10.1124/dmd.108.024570. Epub 2009 Feb 23. Drug Metab Dispos. 2009. PMID: 19237515

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