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1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics.
J Enzyme Inhib Med Chem. 2021 Dec;36(1):1968-1983. doi: 10.1080/14756366.2021.1972993.
J Enzyme Inhib Med Chem. 2021.
PMID: 34482781
Free PMC article.
Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).
Safrygin A, Zhmurov P, Dar'in D, Silonov S, Kasatkina M, Zonis Y, Gureev M, Krasavin M.
Safrygin A, et al. Among authors: zonis y.
J Enzyme Inhib Med Chem. 2021 Dec;36(1):1916-1921. doi: 10.1080/14756366.2021.1969386.
J Enzyme Inhib Med Chem. 2021.
PMID: 34461785
Free PMC article.
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Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.
Issaeva I, Zonis Y, Rozovskaia T, Orlovsky K, Croce CM, Nakamura T, Mazo A, Eisenbach L, Canaani E.
Issaeva I, et al. Among authors: zonis y.
Mol Cell Biol. 2007 Mar;27(5):1889-903. doi: 10.1128/MCB.01506-06. Epub 2006 Dec 18.
Mol Cell Biol. 2007.
PMID: 17178841
Free PMC article.
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