Mak TW - Search Results

1

Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes.

Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A. Ito K, et al. Among authors: mak tw. J Immunol. 2007 Jan 1;178(1):103-10. doi: 10.4049/jimmunol.178.1.103. J Immunol. 2007. PMID: 17182545

2

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

Tang D, Wu D, Hirao A, Lahti JM, Liu L, Mazza B, Kidd VJ, Mak TW, Ingram AJ. Tang D, et al. Among authors: mak tw. J Biol Chem. 2002 Apr 12;277(15):12710-7. doi: 10.1074/jbc.M111598200. Epub 2002 Jan 30. J Biol Chem. 2002. PMID: 11821415 Free article.

3

Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.

Jack MT, Woo RA, Hirao A, Cheung A, Mak TW, Lee PW. Jack MT, et al. Among authors: mak tw. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9825-9. doi: 10.1073/pnas.152053599. Epub 2002 Jul 3. Proc Natl Acad Sci U S A. 2002. PMID: 12097646 Free PMC article.

4

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.

Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW. Hirao A, et al. Among authors: mak tw. Mol Cell Biol. 2002 Sep;22(18):6521-32. doi: 10.1128/MCB.22.18.6521-6532.2002. Mol Cell Biol. 2002. PMID: 12192050 Free PMC article.

5

Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.

Cheung AM, Hande MP, Jalali F, Tsao MS, Skinnider B, Hirao A, McPherson JP, Karaskova J, Suzuki A, Wakeham A, You-Ten A, Elia A, Squire J, Bristow R, Hakem R, Mak TW. Cheung AM, et al. Among authors: mak tw. Cancer Res. 2002 Nov 1;62(21):6194-204. Cancer Res. 2002. PMID: 12414647

6

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

Keramaris E, Hirao A, Slack RS, Mak TW, Park DS. Keramaris E, et al. Among authors: mak tw. J Biol Chem. 2003 Sep 26;278(39):37782-9. doi: 10.1074/jbc.M304049200. Epub 2003 Jul 11. J Biol Chem. 2003. PMID: 12857758 Free article.

7

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.

Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Hamaguchi I, Nomiyama K, Hosokawa K, Sakurada K, Nakagata N, Ikeda Y, Mak TW, Suda T. Ito K, et al. Among authors: mak tw. Nature. 2004 Oct 21;431(7011):997-1002. doi: 10.1038/nature02989. Nature. 2004. PMID: 15496926

8

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.

Zaugg K, Su YW, Reilly PT, Moolani Y, Cheung CC, Hakem R, Hirao A, Liu Q, Elledge SJ, Mak TW. Zaugg K, et al. Among authors: mak tw. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3805-10. doi: 10.1073/pnas.0611584104. Epub 2007 Feb 26. Proc Natl Acad Sci U S A. 2007. PMID: 17360434 Free PMC article.

9

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila.

Peters M, DeLuca C, Hirao A, Stambolic V, Potter J, Zhou L, Liepa J, Snow B, Arya S, Wong J, Bouchard D, Binari R, Manoukian AS, Mak TW. Peters M, et al. Among authors: mak tw. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11305-10. doi: 10.1073/pnas.172382899. Epub 2002 Aug 9. Proc Natl Acad Sci U S A. 2002. PMID: 12172011 Free PMC article.

10

The inducible costimulator plays the major costimulatory role in humoral immune responses in the absence of CD28.

Suh WK, Tafuri A, Berg-Brown NN, Shahinian A, Plyte S, Duncan GS, Okada H, Wakeham A, Odermatt B, Ohashi PS, Mak TW. Suh WK, et al. Among authors: mak tw. J Immunol. 2004 May 15;172(10):5917-23. doi: 10.4049/jimmunol.172.10.5917. J Immunol. 2004. PMID: 15128772

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