Gray NS - Search Results

1

Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

Galkin AV, Melnick JS, Kim S, Hood TL, Li N, Li L, Xia G, Steensma R, Chopiuk G, Jiang J, Wan Y, Ding P, Liu Y, Sun F, Schultz PG, Gray NS, Warmuth M. Galkin AV, et al. Among authors: gray ns. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):270-5. doi: 10.1073/pnas.0609412103. Epub 2006 Dec 21. Proc Natl Acad Sci U S A. 2007. PMID: 17185414 Free PMC article.

2

CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation.

Brooks EE, Gray NS, Joly A, Kerwar SS, Lum R, Mackman RL, Norman TC, Rosete J, Rowe M, Schow SR, Schultz PG, Wang X, Wick MM, Shiffman D. Brooks EE, et al. Among authors: gray ns. J Biol Chem. 1997 Nov 14;272(46):29207-11. doi: 10.1074/jbc.272.46.29207. J Biol Chem. 1997. PMID: 9360999 Free article.

3

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190 Free article.

4

A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts.

Rosania GR, Merlie J Jr, Gray N, Chang YT, Schultz PG, Heald R. Rosania GR, et al. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4797-802. doi: 10.1073/pnas.96.9.4797. Proc Natl Acad Sci U S A. 1999. PMID: 10220373 Free PMC article.

5

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Among authors: gray ns. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538

6

A chemical switch for inhibitor-sensitive alleles of any protein kinase.

Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. Bishop AC, et al. Among authors: gray ns. Nature. 2000 Sep 21;407(6802):395-401. doi: 10.1038/35030148. Nature. 2000. PMID: 11014197

7

Design of allele-specific protein methyltransferase inhibitors.

Lin Q, Jiang F, Schultz PG, Gray NS. Lin Q, et al. Among authors: gray ns. J Am Chem Soc. 2001 Nov 28;123(47):11608-13. doi: 10.1021/ja011423j. J Am Chem Soc. 2001. PMID: 11716715

8

Solid-phase synthesis of 2,3,5-trisubstituted indoles.

Wu TY, Ding S, Gray NS, Schultz PG. Wu TY, et al. Among authors: gray ns. Org Lett. 2001 Nov 29;3(24):3827-30. doi: 10.1021/ol016525t. Org Lett. 2001. PMID: 11720546

9

A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines.

Ding S, Gray NS, Ding Q, Schultz PG. Ding S, et al. Among authors: gray ns. J Org Chem. 2001 Nov 30;66(24):8273-6. doi: 10.1021/jo016010f. J Org Chem. 2001. PMID: 11722241 No abstract available.

10

A combinatorial scaffold approach toward kinase-directed heterocycle libraries.

Ding S, Gray NS, Wu X, Ding Q, Schultz PG. Ding S, et al. Among authors: gray ns. J Am Chem Soc. 2002 Feb 27;124(8):1594-6. doi: 10.1021/ja0170302. J Am Chem Soc. 2002. PMID: 11853431

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