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An approach to speed up the isolation of hydrophilic metabolites from natural sources at semipreparative level by using a hydrophilic-lipophilic balance/mixed-mode strong cation exchange-high-performance liquid chromatography/mass spectrometry system.
Espada A, Anta C, Bragado A, Rodríguez J, Jiménez C. Espada A, et al. J Chromatogr A. 2011 Apr 1;1218(13):1790-4. doi: 10.1016/j.chroma.2011.01.072. Epub 2011 Jan 31. J Chromatogr A. 2011. PMID: 21329935
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