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N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3.
Angell RM, Atkinson FL, Brown MJ, Chuang TT, Christopher JA, Cichy-Knight M, Dunn AK, Hightower KE, Malkakorpi S, Musgrave JR, Neu M, Rowland P, Shea RL, Smith JL, Somers DO, Thomas SA, Thompson G, Wang R. Angell RM, et al. Among authors: musgrave jr. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1296-301. doi: 10.1016/j.bmcl.2006.12.003. Epub 2006 Dec 15. Bioorg Med Chem Lett. 2007. PMID: 17194588
1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3.
Christopher JA, Atkinson FL, Bax BD, Brown MJ, Champigny AC, Chuang TT, Jones EJ, Mosley JE, Musgrave JR. Christopher JA, et al. Among authors: musgrave jr. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2230-4. doi: 10.1016/j.bmcl.2009.02.098. Epub 2009 Feb 28. Bioorg Med Chem Lett. 2009. PMID: 19303774
Piperidine-derived gamma-secretase modulators.
Hall A, Elliott RL, Giblin GM, Hussain I, Musgrave J, Naylor A, Sasse R, Smith B. Hall A, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1306-11. doi: 10.1016/j.bmcl.2009.08.072. Epub 2009 Aug 23. Bioorg Med Chem Lett. 2010. PMID: 20056541