Schaefer RM - Search Results

1

Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.

Schaefer L, Tsalastra W, Babelova A, Baliova M, Minnerup J, Sorokin L, Gröne HJ, Reinhardt DP, Pfeilschifter J, Iozzo RV, Schaefer RM. Schaefer L, et al. Among authors: schaefer rm. Am J Pathol. 2007 Jan;170(1):301-15. doi: 10.2353/ajpath.2007.060497. Am J Pathol. 2007. PMID: 17200203 Free PMC article.

2

Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction.

Schaefer L, Macakova K, Raslik I, Micegova M, Gröne HJ, Schönherr E, Robenek H, Echtermeyer FG, Grässel S, Bruckner P, Schaefer RM, Iozzo RV, Kresse H. Schaefer L, et al. Among authors: schaefer rm. Am J Pathol. 2002 Mar;160(3):1181-91. doi: 10.1016/S0002-9440(10)64937-1. Am J Pathol. 2002. PMID: 11891213 Free PMC article.

3

Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury.

Schaefer L, Mihalik D, Babelova A, Krzyzankova M, Gröne HJ, Iozzo RV, Young MF, Seidler DG, Lin G, Reinhardt DP, Schaefer RM. Schaefer L, et al. Among authors: schaefer rm. Am J Pathol. 2004 Aug;165(2):383-96. doi: 10.1016/S0002-9440(10)63305-6. Am J Pathol. 2004. PMID: 15277214 Free PMC article.

4

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages.

Schaefer L, Babelova A, Kiss E, Hausser HJ, Baliova M, Krzyzankova M, Marsche G, Young MF, Mihalik D, Götte M, Malle E, Schaefer RM, Gröne HJ. Schaefer L, et al. Among authors: schaefer rm. J Clin Invest. 2005 Aug;115(8):2223-33. doi: 10.1172/JCI23755. Epub 2005 Jul 14. J Clin Invest. 2005. PMID: 16025156 Free PMC article.

5

Proteoglycans: from structural compounds to signaling molecules.

Schaefer L, Schaefer RM. Schaefer L, et al. Among authors: schaefer rm. Cell Tissue Res. 2010 Jan;339(1):237-46. doi: 10.1007/s00441-009-0821-y. Epub 2009 Jun 10. Cell Tissue Res. 2010. PMID: 19513755 Review.

6

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Gröne HJ, Schaefer L. Babelova A, et al. Among authors: schaefer l, schaefer rm. J Biol Chem. 2009 Sep 4;284(36):24035-48. doi: 10.1074/jbc.M109.014266. Epub 2009 Jul 15. J Biol Chem. 2009. PMID: 19605353 Free PMC article.

7

Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.

Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L. Merline R, et al. Among authors: schaefer rm. Sci Signal. 2011 Nov 15;4(199):ra75. doi: 10.1126/scisignal.2001868. Sci Signal. 2011. PMID: 22087031 Free PMC article.

8

Small proteoglycans of normal adult human kidney: distinct expression patterns of decorin, biglycan, fibromodulin, and lumican.

Schaefer L, Gröne HJ, Raslik I, Robenek H, Ugorcakova J, Budny S, Schaefer RM, Kresse H. Schaefer L, et al. Among authors: schaefer rm. Kidney Int. 2000 Oct;58(4):1557-68. doi: 10.1046/j.1523-1755.2000.00317.x. Kidney Int. 2000. PMID: 11012890 Free article.

9

Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin.

Schaefer L, Raslik I, Grone HJ, Schonherr E, Macakova K, Ugorcakova J, Budny S, Schaefer RM, Kresse H. Schaefer L, et al. Among authors: schaefer rm. FASEB J. 2001 Mar;15(3):559-61. doi: 10.1096/fj.00-0493fje. Epub 2001 Jan 19. FASEB J. 2001. PMID: 11259366

10

Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration.

Merline R, Lazaroski S, Babelova A, Tsalastra-Greul W, Pfeilschifter J, Schluter KD, Gunther A, Iozzo RV, Schaefer RM, Schaefer L. Merline R, et al. Among authors: schaefer l, schaefer rm. J Physiol Pharmacol. 2009 Oct;60 Suppl 4(Suppl 4):5-13. J Physiol Pharmacol. 2009. PMID: 20083846 Free PMC article.

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