Micklefield J - Search Results

1

Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties.

Tan TH, Worthington RJ, Pritchard RG, Morral J, Micklefield J. Tan TH, et al. Among authors: micklefield j. Org Biomol Chem. 2007 Jan 21;5(2):239-48. doi: 10.1039/b613384n. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205167

2

Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine-amide oligonucleotide mimic (POM).

Hickman DT, King PM, Slater JM, Cooper MA, Micklefield J. Hickman DT, et al. Among authors: micklefield j. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1169-72. doi: 10.1081/NCN-100002512. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562979

3

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM).

Hickman DT, Tan TH, Morral J, King PM, Cooper MA, Micklefield J. Hickman DT, et al. Among authors: micklefield j. Org Biomol Chem. 2003 Oct 7;1(19):3277-92. doi: 10.1039/b306156f. Org Biomol Chem. 2003. PMID: 14584791

4

Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM).

Tan TH, Hickman DT, Morral J, Beadham IG, Micklefield J. Tan TH, et al. Among authors: micklefield j. Chem Commun (Camb). 2004 Mar 7;(5):516-7. doi: 10.1039/b315768g. Epub 2004 Jan 28. Chem Commun (Camb). 2004. PMID: 14973585

5

Stereospecific backbone methylation of pyrrolidine-amide oligonucleotide mimics (POM).

Khan AI, Tan TH, Micklefield J. Khan AI, et al. Among authors: micklefield j. Chem Commun (Camb). 2006 Apr 7;(13):1436-8. doi: 10.1039/b518171b. Epub 2006 Feb 23. Chem Commun (Camb). 2006. PMID: 16550292

6

Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties.

Worthington RJ, O'Rourke AP, Morral J, Tan TH, Micklefield J. Worthington RJ, et al. Among authors: micklefield j. Org Biomol Chem. 2007 Jan 21;5(2):249-59. doi: 10.1039/b613386j. Epub 2006 Dec 1. Org Biomol Chem. 2007. PMID: 17205168

7

NMR confirmation that tryptophan dehydrogenation occurs with syn stereochemistry during the biosynthesis of CDA in Streptomyces coelicolor.

Amir-Heidari B, Micklefield J. Amir-Heidari B, et al. Among authors: micklefield j. J Org Chem. 2007 Nov 9;72(23):8950-3. doi: 10.1021/jo701660v. Epub 2007 Oct 11. J Org Chem. 2007. PMID: 17929869

8

RNA-selective cross-pairing of backbone-extended pyrrolidine-amide oligonucleotide mimics (bePOMs).

Worthington RJ, Bell NM, Wong R, Micklefield J. Worthington RJ, et al. Among authors: micklefield j. Org Biomol Chem. 2008 Jan 7;6(1):92-103. doi: 10.1039/b714580m. Epub 2007 Nov 1. Org Biomol Chem. 2008. PMID: 18075653

9

Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues.

Amir-Heidari B, Thirlway J, Micklefield J. Amir-Heidari B, et al. Among authors: micklefield j. Org Biomol Chem. 2008 Mar 21;6(6):975-8. doi: 10.1039/b718766c. Epub 2008 Feb 11. Org Biomol Chem. 2008. PMID: 18327318

10

Site-selective immobilisation of functional enzymes on to polystyrene nanoparticles.

Wong LS, Okrasa K, Micklefield J. Wong LS, et al. Among authors: micklefield j. Org Biomol Chem. 2010 Feb 21;8(4):782-7. doi: 10.1039/b916773k. Epub 2009 Dec 23. Org Biomol Chem. 2010. PMID: 20135034

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