Shimozono R - Search Results

1

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.

Takeda K, Shimozono R, Noguchi T, Umeda T, Morimoto Y, Naguro I, Tobiume K, Saitoh M, Matsuzawa A, Ichijo H. Takeda K, et al. Among authors: shimozono r. J Biol Chem. 2007 Mar 9;282(10):7522-31. doi: 10.1074/jbc.M607177200. Epub 2007 Jan 8. J Biol Chem. 2007. PMID: 17210579 Free article.

2

Apoptosis signal-regulating kinase 1 is crucial for oxidative stress-induced but not for osmotic stress-induced hepatocyte cell death.

Taki K, Shimozono R, Kusano H, Suzuki N, Shinjo K, Eda H. Taki K, et al. Among authors: shimozono r. Life Sci. 2008 Dec 19;83(25-26):859-64. doi: 10.1016/j.lfs.2008.10.004. Epub 2008 Oct 21. Life Sci. 2008. PMID: 18983857

3

Orally-administered caspase inhibitor PF-03491390 is retained in the liver for prolonged periods with low systemic exposure, exerting a hepatoprotective effect against alpha-fas-induced liver injury in a mouse model.

Ueno Y, Ohmi T, Yamamoto M, Kato N, Moriguchi Y, Kojima M, Shimozono R, Suzuki S, Matsuura T, Eda H. Ueno Y, et al. Among authors: shimozono r. J Pharmacol Sci. 2007 Oct;105(2):201-5. doi: 10.1254/jphs.sc0070207. Epub 2007 Oct 6. J Pharmacol Sci. 2007. PMID: 17928737 Free article.

4

Interferon-β Mediates Signaling Pathways Uniquely Regulated in Hepatic Stellate Cells and Attenuates the Progression of Hepatic Fibrosis in a Dietary Mouse Model.

Shimozono R, Nishimura K, Akiyama H, Funamoto S, Izawa A, Sai T, Kunita K, Kainoh M, Suzuki T, Kawada N. Shimozono R, et al. J Interferon Cytokine Res. 2015 Jun;35(6):464-73. doi: 10.1089/jir.2014.0096. Epub 2015 Feb 25. J Interferon Cytokine Res. 2015. PMID: 25715168 Free PMC article.

5

Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model.

Shimozono R, Asaoka Y, Yoshizawa Y, Aoki T, Noda H, Yamada M, Kaino M, Mochizuki H. Shimozono R, et al. Mol Pharmacol. 2013 Jul;84(1):62-70. doi: 10.1124/mol.112.084269. Epub 2013 Apr 16. Mol Pharmacol. 2013. PMID: 23592516

6

Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus.

Tsuge M, Uchida T, Hiraga N, Kan H, Makokha GN, Abe-Chayama H, Miki D, Imamura M, Ochi H, Hayes CN, Shimozono R, Iwamura T, Narumi H, Suzuki T, Kainoh M, Taniguchi T, Chayama K. Tsuge M, et al. Among authors: shimozono r. Antimicrob Agents Chemother. 2017 May 24;61(6):e00183-17. doi: 10.1128/AAC.00183-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28373196 Free PMC article.

7

Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation.

Satoh M, Saburi H, Tanaka T, Matsuura Y, Naitow H, Shimozono R, Yamamoto N, Inoue H, Nakamura N, Yoshizawa Y, Aoki T, Tanimura R, Kunishima N. Satoh M, et al. Among authors: shimozono r. FEBS Open Bio. 2015 Jun 30;5:557-70. doi: 10.1016/j.fob.2015.06.011. eCollection 2015. FEBS Open Bio. 2015. PMID: 26199865 Free PMC article.

8

Discovery of Peripheral κ-Opioid Receptor Agonists as Novel Analgesics.

Suzuki S, Sugawara Y, Inada H, Tsuji R, Inoue A, Tanimura R, Shimozono R, Konno M, Ohyama T, Higashi E, Sakai C, Kawai K. Suzuki S, et al. Among authors: shimozono r. Chem Pharm Bull (Tokyo). 2017;65(11):1085-1088. doi: 10.1248/cpb.c17-00555. Chem Pharm Bull (Tokyo). 2017. PMID: 29093296 Free article.

9

TXB-001, a newly-developed polymer-conjugated anthracycline: Significantly lower adverse effects in animal models of alopecia and hand-foot syndrome.

Hirakata M, Tomikawa E, Sakai C, Uchida M, Okano T, Shimozono R, Kawai M, Itaba S, Munakata L, Suzuki R, Oshida K. Hirakata M, et al. Among authors: shimozono r. Toxicol Appl Pharmacol. 2024 Apr;485:116912. doi: 10.1016/j.taap.2024.116912. Epub 2024 Mar 22. Toxicol Appl Pharmacol. 2024. PMID: 38521368

10

Extracorporeal shockwave therapy for the treatment of scaphoid delayed union in a tennis player: A case report.

Shimozono R, Nakatani T, Hiroshima Y, Takeuchi M, Onga T. Shimozono R, et al. Trauma Case Rep. 2022 Mar 23;39:100642. doi: 10.1016/j.tcr.2022.100642. eCollection 2022 Jun. Trauma Case Rep. 2022. PMID: 35345782 Free PMC article.

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