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Local Adjuvant Treatment with Low-Dose CpG-B Offers Durable Protection against Disease Recurrence in Clinical Stage I-II Melanoma: Data from Two Randomized Phase II Trials.
Koster BD, van den Hout MFCM, Sluijter BJR, Molenkamp BG, Vuylsteke RJCLM, Baars A, van Leeuwen PAM, Scheper RJ, Petrousjka van den Tol M, van den Eertwegh AJM, de Gruijl TD. Koster BD, et al. Among authors: van leeuwen pam. Clin Cancer Res. 2017 Oct 1;23(19):5679-5686. doi: 10.1158/1078-0432.CCR-17-0944. Clin Cancer Res. 2017. PMID: 28972083 Clinical Trial.
Absence of Granzyme B positive tumour-infiltrating lymphocytes in primary melanoma excisional biopsies is strongly associated with the presence of sentinel lymph node metastasis.
van Houdt IS, Sluijter BJ, van Leeuwen PA, Moesbergen LM, Hooijberg E, Meijer CJ, de Gruijl TD, Oudejans JJ, Boven E. van Houdt IS, et al. Among authors: van leeuwen pa. Cell Oncol. 2009;31(5):407-13. doi: 10.3233/CLO-2009-0485. Cell Oncol. 2009. PMID: 19759420 Free PMC article.
4-1BB-mediated expansion affords superior detection of in vivo primed effector memory CD8+ T cells from melanoma sentinel lymph nodes.
Sluijter BJ, van den Hout MF, Stam AG, Lougheed SM, Suhoski MM, van den Eertwegh AJ, van den Tol MP, van Leeuwen PA, Meijer S, Scheper RJ, June CH, de Gruijl TD, Santegoets SJ. Sluijter BJ, et al. Among authors: van den hout mf, van den tol mp, van den eertwegh aj, van leeuwen pa. Clin Immunol. 2010 Nov;137(2):221-33. doi: 10.1016/j.clim.2010.07.009. Epub 2010 Aug 13. Clin Immunol. 2010. PMID: 20708974
256 results