Hwang CB - Search Results

1

Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication.

Jiang C, Hwang YT, Randell JC, Coen DM, Hwang CB. Jiang C, et al. Among authors: hwang cb. J Virol. 2007 Apr;81(7):3495-502. doi: 10.1128/JVI.02359-06. Epub 2007 Jan 17. J Virol. 2007. PMID: 17229696 Free PMC article.

2

Detection of mutations within the thymidine kinase gene of herpes simplex virus type 1 by denaturing gradient gel electrophoresis.

Lu Q, Hwang YT, Hwang CB. Lu Q, et al. Among authors: hwang yt, hwang cb. J Virol Methods. 2002 Jan;99(1-2):1-7. doi: 10.1016/s0166-0934(01)00388-3. J Virol Methods. 2002. PMID: 11684298

3

Replication fidelity of the supF gene integrated in the thymidine kinase locus of herpes simplex virus type 1.

Hwang YT, Liu BY, Hwang CB. Hwang YT, et al. Among authors: hwang cb. J Virol. 2002 Apr;76(8):3605-14. doi: 10.1128/jvi.76.8.3605-3614.2002. J Virol. 2002. PMID: 11907200 Free PMC article.

4

Mutation spectra of herpes simplex virus type 1 thymidine kinase mutants.

Lu Q, Hwang YT, Hwang CB. Lu Q, et al. Among authors: hwang yt, hwang cb. J Virol. 2002 Jun;76(11):5822-8. doi: 10.1128/jvi.76.11.5822-5828.2002. J Virol. 2002. PMID: 11992012 Free PMC article.

5

Thymidine kinase of herpes simplex virus type 1 strain KOS lacks mutator activity.

Hwang YT, Wang YA, Lu Q, Hwang CB. Hwang YT, et al. Among authors: hwang cb. Virology. 2003 Jan 20;305(2):388-96. doi: 10.1006/viro.2002.1776. Virology. 2003. PMID: 12573584 Free article.

6

Exonuclease-deficient polymerase mutant of herpes simplex virus type 1 induces altered spectra of mutations.

Hwang YT, Hwang CB. Hwang YT, et al. Among authors: hwang cb. J Virol. 2003 Mar;77(5):2946-55. doi: 10.1128/jvi.77.5.2946-2955.2003. J Virol. 2003. PMID: 12584319 Free PMC article.

7

A point mutation within conserved region VI of herpes simplex virus type 1 DNA polymerase confers altered drug sensitivity and enhances replication fidelity.

Hwang YT, Zuccola HJ, Lu Q, Hwang CB. Hwang YT, et al. Among authors: hwang cb. J Virol. 2004 Jan;78(2):650-7. doi: 10.1128/jvi.78.2.650-657.2004. J Virol. 2004. PMID: 14694096 Free PMC article.

8

Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.

Randell JC, Komazin G, Jiang C, Hwang CB, Coen DM. Randell JC, et al. Among authors: hwang cb. J Virol. 2005 Sep;79(18):12025-34. doi: 10.1128/JVI.79.18.12025-12034.2005. J Virol. 2005. PMID: 16140778 Free PMC article.

9

Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis.

Jiang C, Hwang YT, Wang G, Randell JC, Coen DM, Hwang CB. Jiang C, et al. Among authors: hwang cb. J Virol. 2007 Nov;81(21):12077-9. doi: 10.1128/JVI.01133-07. Epub 2007 Aug 22. J Virol. 2007. PMID: 17715219 Free PMC article.

10

The enhanced DNA replication fidelity of a mutant herpes simplex virus type 1 DNA polymerase is mediated by an improved nucleotide selectivity and reduced mismatch extension ability.

Tian W, Hwang YT, Hwang CB. Tian W, et al. Among authors: hwang cb. J Virol. 2008 Sep;82(17):8937-41. doi: 10.1128/JVI.00911-08. Epub 2008 Jul 2. J Virol. 2008. PMID: 18596099 Free PMC article.

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